| Type | Description |
|---|---|
| Definition | G protein-coupled receptor 17 |
| Date | Results | Publications |
|---|---|---|
| 2021-02-02 13:26:00 | FLIM-FRET-Based Structural Characterization of a Class-A GPCR Dimer in the | 32553728 |
| 2019-06-01 10:28:00 | GPR17 may mediate hypoxia injury in RGC-5 cells, while the knockdown of GPR17 can reduce the hypoxia injury | 30693690 |
| 2018-07-14 11:43:00 | In silico and ex vivo validation experiments provided the deep understanding of ligand binding with GPR17 and the present findings reported here may lead to use these two compounds as a potential activator of GPR17 for therapeutic intervention. | 28827203 |
| 2018-01-06 11:45:00 | Results show a crucial role of SNX27 in modulating GPR17 levels by means of a post-translational mechanism and highlights the relationship between the trafficking of the receptor through the endomembrane system and oligodendrocyte differentiation; and provide novel evidence of impairment of GPR17 expression and oligodendrocyte maturation in a mouse model of Down syndrome that is characterized by SNX27 down-regulation. | 27270750 |
| 2017-05-13 13:42:00 | uracil nucleotides and cysteinyl leukotrienes do not activate human, mouse, or rat GPR17 in various cellular backgrounds. | 28254957 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
GPR17_HUMAN,
G4XH68_HUMAN
UniprotKB:
Q13304,
G4XH68
UniParc:
UPI000002AAB1,
UPI0000050432
EMBL:
JF810891,
CH471103,
AK313949,
BC031653,
U33447,
BC039595,
Y12546,
Z94154,
AK292725,
Z94155
Ensembl:
ENSG00000144230
KO:
hsa:2840
|
| Nucleutide sequences |
EMBL-CDS:
CAB08108.1,
EAW95337.1,
BAF85414.1,
BAG36667.1,
AAB16746.1,
AAH31653.1,
CAB08107.1,
CAA73144.1,
AEP43758.1
Ensembl_TRS:
ENST00000393018,
ENST00000544369,
ENST00000272644
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000272644,
ENSP00000376741,
ENSP00000442982
RefSeq:
NP_001154888.1,
NP_005282.1,
NP_001154889.1,
XP_016859322.1,
NP_001154887.1
|
| Others |
UniRef100:
UniRef100_Q13304
UniRef90:
UniRef90_Q13304
UniRef50:
UniRef50_Q13304
UniGene:
Hs.46453,
Hs.736277
CCDS:
CCDS2148.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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