Type | Description |
---|---|
Definition | G protein-coupled receptor 12 |
Date | Results | Publications |
---|---|---|
2017-10-28 10:52:00 | Since we have demonstrated that CBD is an inverse agonist for GPR12, this provides novel mechanism of action for CBD, and an initial chemical scaffold upon which highly potent and efficacious agents acting on GPR12 may be developed with the ultimate goal of blocking cancer metastasis. | 28888984 |
2012-10-13 11:28:00 | GPR12 may play a role in cell proliferation and survival | 22430950 |
2010-01-21 00:00:00 | control of gene expression in vascular endothelial cells in the presence of fluid shear stress and classifies it as a sphingosine 1-phosphate receptor | 12649592 |
Type | IDs |
---|---|
Synonymous | GPCR12, GPCR21, PPP1R84 |
Gene |
UniProtKB-ID:
GPR12_HUMAN,
A8K2F5_HUMAN,
B4DG25_HUMAN
UniprotKB:
P47775,
A8K2F5,
B4DG25
UniParc:
UPI00017A6DD7,
UPI000003EC24
EMBL:
BC067448,
CH471075,
BC112146,
AK312602,
HQ995525,
AK290220,
U18548,
BC067452,
AK294378,
BC112144,
AL159978
Ensembl:
ENSG00000132975
KO:
hsa:2835
|
Nucleutide sequences |
EMBL-CDS:
AAH67452.1,
AAI12147.1,
AAI12145.1,
AAH67448.1,
AAA91630.1,
BAG35492.1,
EAX08390.1,
BAF82909.1,
ADZ31970.1,
BAG57636.1
Gene_ORFName:
hCG_1644664
Ensembl_TRS:
ENST00000405846,
ENST00000381436
|
Protein sequencees |
Ensembl_PRO:
ENSP00000370844,
ENSP00000384932
RefSeq:
NP_005279.1,
XP_005266417.1
|
Others |
UniRef100:
UniRef100_P47775
UniRef90:
UniRef90_P47775
UniRef50:
UniRef50_P35413
UniGene:
Hs.123034
CCDS:
CCDS9319.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
---|---|---|---|
28888984 |
Cannabidiol, a novel inverse agonist for GPR12. Biochem. Biophys. Res. Commun. Kevin J Brown , Alyssa S Laun , Zhao-Hui Song |
2017-11-04 | - |
22430950 |
Involvement of GPR12 in the regulation of cell proliferation and survival. Mol. Cell. Biochem. Xiaoming Lu , Ning Zhang , Bo Meng , Suzhen Dong , Yinghe Hu |
2012-07-01 | - |
21832049 |
J Biol Chem Judit Oláh , Orsolya Vincze , Dezsõ Virók , Dóra Simon , Zsolt Bozsó , Natália Tõkési , István Horváth , Emma Hlavanda , János Kovács , Anna Magyar , Mária Szũcs , Ferenc Orosz , Botond Penke , Judit Ovádi |
2011-09-30 | - |
21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
19389623 |
Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem. Biol. Annick Hendrickx , Monique Beullens , Hugo Ceulemans , Tom Den Abt , Aleyde Van Eynde , Emilia Nicolaescu , Bart Lesage , Mathieu Bollen |
2009-04-24 |
FARP1,
MPHOSPH10,
CD2BP2,
CENPE,
KDM5B,
LMTK3,
ELFN2,
PPP1R27,
TMEM132D,
WDR81,
PPP1R21,
ZSWIM3,
PPP1R36,
SH3RF2,
SPRED1,
CNST,
DLG2,
DLG3,
PPP1R32,
PPP1R35,
RRP1B,
FKBP15,
RPGRIP1L,
RIMBP2,
ZBTB38,
TRPC4AP,
SACS,
PCDH11X,
GPR12,
PPP1R37,
TRIM42,
UBN1,
TMEM225,
ITPR3,
GRXCR1,
ELFN1,
MAP1B,
MCM7,
MKI67,
MYO1D,
ORC5,
VPS54,
ZFYVE1,
KCNK10,
HYDIN,
SYTL2,
CHCHD3,
PPP1CA,
GPATCH2,
CEP192,
CASC1,
CASC5,
ARFGEF3,
PHRF1,
CAMSAP3,
SLC7A14,
TSKS,
SH2D4A,
PCIF1,
RBM26,
CSMD1,
DDX31,
WNK1,
TSC2,
CSRNP3,
PREX2,
CSRNP2,
ELL,
CCDC8,
ZCCHC9,
CHCHD6,
NIFK,
SPOCD1,
PKMYT1,
TMEM132C,
KIAA0430,
DZIP3,
SFI1,
SPATA2,
PPP1R26,
PPP1CA
|
15489334 |
Genome Res. Daniela S Gerhard , Lukas Wagner , Elise A Feingold , Carolyn M Shenmen , Lynette H Grouse , Greg Schuler , Steven L Klein , Susan Old , Rebekah Rasooly , Peter Good , Mark Guyer , Allison M Peck , Jeffery G Derge , David Lipman , Francis S Collins , Wonhee Jang , Steven Sherry , Mike Feolo , Leonie Misquitta , Eduardo Lee , Kirill Rotmistrovsky , Susan F Greenhut , Carl F Schaefer , Kenneth Buetow , Tom I Bonner , David Haussler , Jim Kent , Mark Kiekhaus , Terry Furey , Michael Brent , Christa Prange , Kirsten Schreiber , Nicole Shapiro , Narayan K Bhat , Ralph F Hopkins , Florence Hsie , Tom Driscoll , M Bento Soares , Tom L Casavant , Todd E Scheetz , Michael J Brown-stein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Yulan Piao , Dawood B Dudekula , Minoru S H Ko , Koichi Kawakami , Yutaka Suzuki , Sumio Sugano , C E Gruber , M R Smith , Blake Simmons , Troy Moore , Richard Waterman , Stephen L Johnson , Yijun Ruan , Chia Lin Wei , S Mathavan , Preethi H Gunaratne , Jiaqian Wu , Angela M Garcia , Stephen W Hulyk , Edwin Fuh , Ye Yuan , Anna Sneed , Carla Kowis , Anne Hodgson , Donna M Muzny , John McPherson , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madari , Alice C Young , Keith D Wetherby , Steven J Granite , Peggy N Kwong , Charles P Brinkley , Russell L Pearson , Gerard G Bouffard , Robert W Blakesly , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Malachi Griffith , Obi L Griffith , Martin I Krzywinski , Nancy Liao , Ryan Morin , Ryan Morrin , Diana Palmquist , Anca S Petrescu , Ursula Skalska , Duane E Smailus , Jeff M Stott , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Robert A Holt , Agnes Baross , Marco A Marra , Sandra Clifton , Kathryn A Makowski , Stephanie Bosak , Joel Malek , MGC Project Team |
2004-10-01 |
Ldlrap1,
Dnajc3,
Rnaset2a,
Btnl1,
Isg15,
Cyp3a41b,
Ly6c2,
Ccl21b,
Eif3j2,
Mup18,
Lrrc19,
Rcc1,
1700047I17Rik2,
Pcsk9,
Adat3,
Tdrd7,
Sco2,
Gpr153,
Pafah2,
Gm44504,
H6pd,
Adprhl2,
Gpn2,
Rusc2,
Stx12,
Ppp1r8,
Smpdl3b,
Fam46b,
Bsdc1,
Slc44a1,
Zfand2a,
Rubcn,
Kifc1,
Pifo,
C030017K20Rik,
Cbarp,
Rpl5,
Micalcl,
Atg14,
Lrrc8c,
Noc4l,
Nsun5,
Psph,
Trrap,
Mapre3,
Ube3c,
Tbc1d14,
Hscb,
Tyw1,
Emilin1,
Rab28,
Pot1a,
Parp11,
Tada3,
Tra2a,
Brk1,
Fbxl14,
Phrf1,
Plekha1,
Gm21975,
Ric8a,
Mob2,
Prkd2,
Ccp110,
Vrk3,
Grwd1,
Nlrp6,
Trim68,
Psip1,
Spred3,
Faap24,
Ints4,
Rrp8,
Unc45a,
Igflr1,
Sf3b3,
D8Ertd738e,
Usb1,
Champ1,
Smim19,
Exoc8,
Gadd45gip1,
Phkb,
Dohh,
Fam192a,
Enkd1,
Taf5l,
Zdhhc7,
Snapc2,
Ak6,
Gpat4,
Dcun1d2,
Ankrd10,
Cog4,
Hinfp,
Lars2,
Xylb,
Imp3,
Cmtm7
|
15057823 |
The DNA sequence and analysis of human chromosome 13. Nature A Dunham , L H Matthews , J Burton , J L Ashurst , K L Howe , K J Ashcroft , D M Beare , D C Burford , S E Hunt , S Griffiths-Jones , M C Jones , S J Keenan , K Oliver , C E Scott , R Ainscough , J P Almeida , K D Ambrose , D T Andrews , R I S Ashwell , A K Babbage , C L Bagguley , J Bailey , R Bannerjee , K F Barlow , K Bates , H Beasley , C P Bird , S Bray-Allen , A J Brown , J Y Brown , W Burrill , C Carder , N P Carter , J C Chapman , M E Clamp , S Y Clark , G Clarke , C M Clee , S C M Clegg , V Cobley , J E Collins , N Corby , G J Coville , P Deloukas , P Dhami , I Dunham , M Dunn , M E Earthrowl , A G Ellington , L Faulkner , A G Frankish , J Frankland , L French , P Garner , J Garnett , J G R Gilbert , C J Gilson , J Ghori , D V Grafham , S M Gribble , C Griffiths , R E Hall , S Hammond , J L Harley , E A Hart , P D Heath , P J Howden , E J Huckle , P J Hunt , A R Hunt , C Johnson , D Johnson , M Kay , A M Kimberley , A King , G K Laird , C J Langford , S Lawlor , D A Leongamornlert , D M Lloyd , C Lloyd , J E Loveland , J Lovell , S Martin , M Mashreghi-Mohammadi , S J McLaren , A McMurray , S Milne , M J F Moore , T Nickerson , S A Palmer , A V Pearce , A I Peck , S Pelan , B Phillimore , K M Porter , C M Rice , S Searle , H K Sehra , R Shownkeen , C D Skuce , M Smith , C A Steward , N Sycamore , J Tester , D W Thomas , A Tracey , A Tromans , B Tubby , M Wall , J M Wallis , A P West , S L Whitehead , D L Willey , L Wilming , P W Wray , M W Wright , L Young , A Coulson , R Durbin , T Hubbard , J E Sulston , S Beck , D R Bentley , J Rogers , M T Ross |
2004-04-01 |
LOC100129307,
CCT5-2P,
GPC6,
FRY,
MBNL2,
FARP1,
LPAR6,
LHFP,
LOC101928697,
TRIM13,
MRPS31,
SPRY2,
SAP18,
TUBGCP3,
PIBF1,
POSTN,
HSPH1,
WASF3,
RCBTB2,
WBP4,
AKAP11,
KLF12,
ADPRHL1,
SLITRK1,
ARL11,
TEX29,
TEX26,
PRR20A,
SPACA7,
COL4A1,
COL4A2,
CPB2,
RNF113B,
PARP4,
B3GLCT,
DACH1,
DGKH,
GPR180,
STOML3,
DCT,
COMMD6,
EFNB2,
ESD,
F7,
AMER2,
USP12,
GSX1,
SKA3,
MICU2,
SPATA13,
LNX2,
FGF9,
FGF14,
GPC5,
FNDC3A,
DIS3,
MYCBP2,
FOXO1,
ZC3H13,
SPG20,
ATP11A,
DOCK9,
TGDS,
ALOX5AP,
ZDHHC20,
PAN3,
SLITRK5,
SACS,
INTS6,
CKAP2,
HS6ST3,
DAOA,
NUFIP1,
GJA3,
GJB2,
OXGR1,
PCDH17,
CHAMP1,
GPR12,
GPR18,
MLNR,
RGCC,
MED4,
DNAJC15,
HTR2A,
UBAC2,
FREM2,
NEK5,
TMEM255B,
SERP2,
LIG4,
ATP4B,
PCDH9,
VPS36,
POLR1D,
CRYL1,
PHF11,
POMP,
UFM1
|
14702039 |
Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. Toshio Ota , Yutaka Suzuki , Tetsuo Nishikawa , Tetsuji Otsuki , Tomoyasu Sugiyama , Ryotaro Irie , Ai Wakamatsu , Koji Hayashi , Hiroyuki Sato , Keiichi Nagai , Kouichi Kimura , Hiroshi Makita , Mitsuo Sekine , Masaya Obayashi , Tatsunari Nishi , Toshikazu Shibahara , Toshihiro Tanaka , Shizuko Ishii , Jun-ichi Yamamoto , Kaoru Saito , Yuri Kawai , Yuko Isono , Yoshitaka Nakamura , Kenji Nagahari , Katsuhiko Murakami , Tomohiro Yasuda , Takao Iwayanagi , Masako Wagatsuma , Akiko Shiratori , Hiroaki Sudo , Takehiko Hosoiri , Yoshiko Kaku , Hiroyo Kodaira , Hiroshi Kondo , Masanori Sugawara , Makiko Takahashi , Katsuhiro Kanda , Takahide Yokoi , Takako Furuya , Emiko Kikkawa , Yuhi Omura , Kumi Abe , Kumiko Kamihara , Naoko Katsuta , Kazuomi Sato , Machiko Tanikawa , Makoto Yamazaki , Ken Ninomiya , Tadashi Ishibashi , Hiromichi Yamashita , Katsuji Murakawa , Kiyoshi Fujimori , Hiroyuki Tanai , Manabu Kimata , Motoji Watanabe , Susumu Hiraoka , Yoshiyuki Chiba , Shinichi Ishida , Yukio Ono , Sumiyo Takiguchi , Susumu Watanabe , Makoto Yosida , Tomoko Hotuta , Junko Kusano , Keiichi Kanehori , Asako Takahashi-Fujii , Hiroto Hara , Tomo-o Tanase , Yoshiko Nomura , Sakae Togiya , Fukuyo Komai , Reiko Hara , Kazuha Takeuchi , Miho Arita , Nobuyuki Imose , Kaoru Musashino , Hisatsugu Yuuki , Atsushi Oshima , Naokazu Sasaki , Satoshi Aotsuka , Yoko Yoshikawa , Hiroshi Matsunawa , Tatsuo Ichihara , Namiko Shiohata , Sanae Sano , Shogo Moriya , Hiroko Momiyama , Noriko Satoh , Sachiko Takami , Yuko Terashima , Osamu Suzuki , Satoshi Nakagawa , Akihiro Senoh , Hiroshi Mizoguchi , Yoshihiro Goto , Fumio Shimizu , Hirokazu Wakebe , Haretsugu Hishigaki , Takeshi Watanabe , Akio Sugiyama , Makoto Takemoto , Bunsei Kawakami , Masaaki Yamazaki , Koji Watanabe , Ayako Kumagai , Shoko Itakura , Yasuhito Fukuzumi , Yoshifumi Fujimori , Megumi Komiyama , Hiroyuki Tashiro , Akira Tanigami , Tsutomu Fujiwara , Toshihide Ono , Katsue Yamada , Yuka Fujii , Kouichi Ozaki , Maasa Hirao , Yoshihiro Ohmori , Ayako Kawabata , Takeshi Hikiji , Naoko Kobatake , Hiromi Inagaki , Yasuko Ikema , Sachiko Okamoto , Rie Okitani , Takuma Kawakami , Saori Noguchi , Tomoko Itoh , Keiko Shigeta , Tadashi Senba , Kyoka Matsumura , Yoshie Nakajima , Takae Mizuno , Misato Morinaga , Masahide Sasaki , Takushi Togashi , Masaaki Oyama , Hiroko Hata , Manabu Watanabe , Takami Komatsu , Junko Mizushima-Sugano , Tadashi Satoh , Yuko Shirai , Yukiko Takahashi , Kiyomi Nakagawa , Koji Okumura , Takahiro Nagase , Nobuo Nomura , Hisashi Kikuchi , Yasuhiko Masuho , Riu Yamashita , Kenta Nakai , Tetsushi Yada , Yusuke Nakamura , Osamu Ohara , Takao Isogai , Sumio Sugano |
2004-01-01 |
Slc9a8,
Nefm,
Hfe2,
AKT3,
ZBTB11-AS1,
LOC100034248,
PDZK1P1,
DDTL,
LOC100049716,
ACOT8,
GNPDA1,
ZBTB33,
GTF2IP4,
POM121C,
ZSCAN30,
SRA1,
SNORD123,
UCKL1-AS1,
ZGLP1,
LOC100125918,
LINC00322,
LOC100127940,
HECW1-IT1,
LOC100127955,
LOC100127972,
LOC100127974,
FAM229A,
LOC100128076,
STAU2-AS1,
LOC100128164,
TMPO-AS1,
LOC100128219,
LOC100128239,
LOC100128253,
TNK2-AS1,
DNM1P35,
LOC100128288,
DLG5-AS1,
LOC100128310,
TRAPPC3L,
FAM83H-AS1,
LOC100128361,
LOC100128364,
FAM225B,
LOC100128386,
LOC100128398,
ASTN2-AS1,
C1orf132,
MYHAS,
LOC100128651,
LINC00476,
SRRM2-AS1,
GPR158-AS1,
LINC01165,
VPS9D1-AS1,
FAM66B,
GATA6-AS1,
LINC01310,
LOC100128979,
LOC100128988,
LOC100129034,
SEMA3F-AS1,
UNQ6494,
LOC100129115,
KHDC1L,
LOC100129175,
MATN1-AS1,
SLC39A12-AS1,
LOC100129297,
LOC100129312,
LINC00484,
LOC100129397,
LOC100129406,
DDC-AS1,
LOC100129434,
LOC100129447,
LOC100129455,
LYRM4-AS1,
ZNF37BP,
LOC100129516,
LOC100129518,
LOC100129540,
LOC100129572,
FAM47E,
LOC100129620,
LOC100129648,
C9orf173-AS1,
LOC100129775,
SLC25A21-AS1,
PCOLCE-AS1,
SCOC-AS1,
LOC100129884,
LOC100129894,
LOC100129917,
LOC100129935,
LOC100130078,
LOC100130111,
MAPT-IT1,
MIR124-2HG
|
12649592 |
Cell. Physiol. Biochem. Kirsten Uhlenbrock , Jochen Huber , Ali Ardati , Andreas E Busch , Evi Kostenis |
2003-01-01 | - |
12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员