| Type | Description |
|---|---|
| Definition | Ras association domain family member 3 |
| Date | Results | Publications |
|---|---|---|
| 2014-10-04 11:00:00 | low expression is associated with malignant phenotypes in non-small cell lung cancer patients | 24246507 |
| 2014-06-14 11:54:00 | Taken together, these findings indicate that the RASSF3 promoter rs6581580 T>G SNP is potentially functional, modulating susceptibility to SCCHN among non-Hispanic whites. | 24295637 |
| 2013-10-19 11:02:00 | hypermethylation-induced RASSF3 silencing plays an important role in the tumorigenesis of pituitary somatotroph adenomas. | 23555615 |
| 2012-08-11 10:24:00 | tumor suppressor activity of RASSF3, which occurs through p53 stabilization and regulation of apoptosis and the cell cycle. | 22593196 |
| 2010-04-07 21:40:00 | Observational study of gene-disease association. (HuGE Navigator) | 20237496 |
| Type | IDs |
|---|---|
| Synonymous | RASSF5 |
| Gene |
UniProtKB-ID:
RASF3_HUMAN
UniprotKB:
Q86WH2
UniParc:
UPI00000622AE,
UPI00000622AF
EMBL:
AY217662,
BC100949,
BC100951,
AY217663
Ensembl:
ENSG00000153179
KO:
hsa:283349
|
| Nucleutide sequences |
EMBL-CDS:
AAO61688.1,
AAI00952.1,
AAI00950.1,
AAO61687.1
Ensembl_TRS:
ENST00000542104,
ENST00000336061,
ENST00000283172
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000336616,
ENSP00000443021,
ENSP00000283172
RefSeq:
XP_011536497.1,
XP_016874671.1,
XP_006719408.1,
NP_835463.1
|
| Others |
UniRef100:
UniRef100_Q86WH2
UniRef90:
UniRef90_Q86WH2
UniRef50:
UniRef50_Q86WH2
UniGene:
Hs.643605
CCDS:
CCDS8969.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 28611215 |
Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown |
2017-06-27 | - |
| 28514442 |
Architecture of the human interactome defines protein communities and disease networks. Nature Edward L Huttlin , Raphael J Bruckner , Joao A Paulo , Joe R Cannon , Lily Ting , Kurt Baltier , Greg Colby , Fana Gebreab , Melanie P Gygi , Hannah Parzen , John Szpyt , Stanley Tam , Gabriela Zarraga , Laura Pontano-Vaites , Sharan Swarup , Anne E White , Devin K Schweppe , Ramin Rad , Brian K Erickson , Robert A Obar , K G Guruharsha , Kejie Li , Spyros Artavanis-Tsakonas , Steven P Gygi , J Wade Harper |
2017-05-25 | - |
| 25900982 |
BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates. Mol Cell Proteomics Etienne Coyaud , Monika Mis , Estelle M N Laurent , Wade H Dunham , Amber L Couzens , Melanie Robitaille , Anne-Claude Gingras , Stephane Angers , Brian Raught |
2015-07-01 | - |
| 26091241 |
DNA Damage Regulates Translation through β-TRCP Targeting of CReP. PLoS Genet Theresa B Loveless , Benjamin R Topacio , Ajay A Vashisht , Shastyn Galaang , Katie M Ulrich , Brian D Young , James A Wohlschlegel , David P Toczyski |
2015-06-01 | - |
| 26673895 |
A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Elife Koray Kırlı , Samir Karaca , Heinz Jürgen Dehne , Matthias Samwer , Kuan Ting Pan , Christof Lenz , Henning Urlaub , Dirk Görlich |
2015-01-01 |
CHA1,
KRR1,
SRO9,
STE50,
RRP7,
RNQ1,
DCC1,
GBP2,
SAT4,
RVS161,
YCR016W,
PWP2,
SSK22,
SOL2,
PAT1,
YCR087C-A,
OCA4,
MOB2,
EPL1,
BUD27,
FRS2,
LOC1,
YFR016C,
LSB3,
RPL2A,
PHO4,
SAP155,
IRC6,
ENT4,
PRP19,
RIX7,
YLL032C,
FRA1,
ISA1,
SPA2,
PUF3,
RPL8B,
NOC3,
SSL1,
SSK1,
NSE1,
RLP24,
SDO1,
ADE16,
RPL15A,
STU2,
RPS0B,
FRS1,
BMT6,
KIN2,
HRT3,
REX3,
YLR108C,
CFT2,
MSL5,
ACE2,
STM1,
YLR157C-A,
APS1,
CBF5,
SWI6,
SKG3,
HCR1,
PWP1,
NOP56,
BUR2,
GPN3,
DBP9,
GCD7,
SGD1,
STE11,
NMD4,
RPS22B,
ROM2,
STP3,
IKI3,
REH1,
AFG2,
UTP21,
ATG17,
TUS1,
MAG2,
ATG23,
RPS1A,
FPR4,
PDP3,
CDC24,
RBG1,
FUN12,
MTW1,
PRP45,
MAK16,
ECM1,
GPB2,
VPS8,
KIN3,
CDC15,
YAT1,
WHI4
|
| 25332235 |
Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase. Mol. Cell. Biol. Tai Young Kim , Priscila F Siesser , Kent L Rossman , Dennis Goldfarb , Kathryn Mackinnon , Feng Yan , XianHua Yi , Michael J MacCoss , Randall T Moon , Channing J Der , Michael B Major |
2015-01-01 |
BCL2L11,
UBE4B,
SSSCA1,
NUDC,
KDM5B,
CLPX,
CHD1,
RASSF1,
TRIM9,
CLTC,
AEBP2,
AMER1,
CTNNA1,
CTNNB1,
USP54,
EML5,
DHX9,
DOCK1,
FLCN,
STOM,
EZH2,
CNOT1,
MAST3,
MAST2,
LPIN1,
FLNC,
BOP1,
FBXW11,
SUZ12,
CBARP,
SUN2,
ARIH1,
MAGI3,
FBXO5,
HBP1,
SND1,
TUBGCP4,
PDCD4,
RASSF3,
ZNF326,
CNOT7,
EEF2K,
HCFC1,
HIVEP1,
HIVEP2,
HNRNPU,
FOXN2,
ILF3,
KIF11,
VSIG8,
LMNA,
LRCH4,
MAX,
ATF4,
NEDD8,
NFE2L2,
NFKB1,
NFKB2,
NRDC,
COPS7A,
LAP3,
PFDN4,
PFDN5,
PLEC,
KCTD5,
USP47,
PTCD3,
MAP1S,
HIST2H4B,
DENND4C,
SCYL2,
ZNF395,
EPB41L5,
CACHD1,
USP37,
NCKAP5L,
PTPN13,
RELA,
REST,
ZNF704,
ELMO2,
CLSPN,
DEPTOR,
SKP1,
STK3,
STK4,
TACC1,
TFAM,
TFAP4,
TIAM1,
TJP1,
TTN,
SKP1P2,
UBC,
WEE1,
YWHAE,
DAP3,
KCTD17,
BORA
|
| 24295637 |
Eur. J. Cancer Hongguang Guo , Hongliang Liu , Jianhua Wei , Yangkai Li , Hongping Yu , Xiaoxiang Guan , Wang Li-E , Guojun Li , Erich M Sturgis , Qingyi Wei , Zhensheng Liu |
2014-02-01 |
RASSF3
|
| 24246507 |
RASSF3 downregulation increases malignant phenotypes of non-small cell lung cancer. Lung Cancer Asuki Fukatsu , Futoshi Ishiguro , Ichidai Tanaka , Takumi Kudo , Kentaro Nakagawa , Keiko Shinjo , Yutaka Kondo , Makiko Fujii , Yoshinori Hasegawa , Kenji Tomizawa , Tetsuya Mitsudomi , Hirotaka Osada , Yutaka Hata , Yoshitaka Sekido |
2014-01-01 |
RASSF3
|
| 24255178 |
Sci Signal Amber L Couzens , James D R Knight , Michelle J Kean , Guoci Teo , Alexander Weiss , Wade H Dunham , Zhen-Yuan Lin , Richard D Bagshaw , Frank Sicheri , Tony Pawson , Jeffrey L Wrana , Hyungwon Choi , Anne-Claude Gingras |
2013-11-19 |
HDAC6,
HDAC5,
AKAP9,
MPHOSPH9,
PATJ,
DCAF7,
DENND4A,
PAK4,
BASP1,
YAP1,
TAB1,
BAIAP2,
PIBF1,
PFDN6,
SORBS1,
IGF2BP2,
PNMA2,
NUDC,
MAP3K2,
KIF1C,
NCKAP1,
SDCCAG3,
TUBGCP2,
RUVBL2,
SUGT1,
YWHAQ,
ILVBL,
KIF2C,
RAB35,
CDC42EP1,
GLMN,
ERLIN2,
RASSF1,
RASSF8,
SNX18,
NACC1,
WDR92,
CNTROB,
AGAP3,
SSX2IP,
AMER1,
DOCK11,
MPP7,
PLEKHA7,
MIPOL1,
CSNK1E,
FBXL16,
CTNNB1,
SPICE1,
CYLD,
RUNDC3B,
AMOT,
AMOTL1,
USP54,
AP2A1,
AP2A2,
AP1B1,
DBN1,
CCDC138,
DDX6,
ECH1,
PGAM5,
EIF4EBP1,
CRTC2,
MARK2,
DMTN,
EPS8,
ACSL3,
LNX2,
FAM83B,
ALDH3A2,
CEP162,
RAB11FIP2,
ANKRD26,
R3HDM2,
PPP6R1,
INPP5F,
RUFY3,
TRIM32,
NINL,
CEP131,
CEP152,
STK38L,
CNOT1,
SAMD4A,
UHRF1BP1L,
ERC1,
FOXO3,
SIPA1L3,
KIF1B,
TNRC6B,
CLASP2,
EPB41L3,
MAST2,
LRCH1,
FAM175B,
TBC1D1,
ANKRD28,
MTCL1
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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