| Type | Description |
|---|---|
| Definition | G protein-coupled receptor 3 |
| Date | Results | Publications |
|---|---|---|
| 2019-10-19 11:30:00 | these results suggest an important role of the allosteric sodium binding site for GPR3 activity and open a possible avenue for the modulation of Abeta production in the Alzheimer's Disease. | 30038319 |
| 2017-10-14 12:45:00 | Results demonstrate that GPR3 signals at the plasma membrane and can be silenced by GRK2/beta-arrestin overexpression. These results also strongly implicate the serine and/or threonine residues in the third intracellular loop in the regulation of GPR3 activity. | 23826079 |
| 2014-05-10 13:55:00 | Gpr3 stimulates Abeta production via interactions with APP and beta-arrestin2. | 24069330 |
| 2013-07-20 11:55:00 | GPR3 is a key factor in the regulation of the nervous system and follicle development.[review] | 23732663 |
| 2012-10-16 09:42:00 | GPR3 is expressed in the ovary and testes, and is necessary for the regulation of meiosis in mouse. | 15591206 |
| Type | IDs |
|---|---|
| Synonymous | ACCA |
| Gene |
UniProtKB-ID:
GPR3_HUMAN,
F1DAM5_HUMAN
UniprotKB:
P46089,
F1DAM5
UniParc:
UPI0000001624
EMBL:
X83956,
AL096774,
AK314868,
AK291185,
CH471059,
HQ709189,
BC032702,
L32831,
U13668,
U18550
Ensembl:
ENSG00000181773
KO:
hsa:2827
|
| Nucleutide sequences |
EMBL-CDS:
AAA73560.1,
BAG37383.1,
AAB60402.1,
BAF83874.1,
AAA64594.1,
AAH32702.1,
CAC18517.1,
EAX07754.1,
CAA58787.1,
ADZ17396.1
Ensembl_TRS:
ENST00000374024
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000363136
RefSeq:
NP_005272.1
|
| Others |
UniRef100:
UniRef100_P46089
UniRef90:
UniRef90_P46089
UniRef50:
UniRef50_P35413
UniGene:
Hs.66542
CCDS:
CCDS303.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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