| Type | Description |
|---|---|
| Definition | solute carrier organic anion transporter family, member 1b2 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:25:00 | Expression of Oatp2 in the Brain and Liver of Alzheimer Disease Mouse Model. | 31967785 |
| 2020-08-01 15:23:00 | This finding is consistent with the metabolism of regorafenib occurring via two competing pathways, and the lack of Oatp1b2 results in decreased clearance of Regorafenib. | 30955241 |
| 2018-04-21 10:15:00 | Experiments testing the cellular uptake of androgens suggest that testosterone is an excellent substrate of OATP1B3 and cells expressing a doxycycline-inducible SLCO1B3 construct had greater uptake of a clinically relevant concentration of 3H-testosterone . When compared with Slco1b2 (-/-) mice, Slco1b2 (-/-)/hSLCO1B3 knockins had greater greater hepatic uptakeand lower plasma exposure to 3H-testosterone | 28389619 |
| 2017-05-13 17:04:00 | important roles for OATP1A/1B in transporter-mediated uptake and disposition of doxorubicin, are reported. | 27777271 |
| 2017-02-18 10:37:00 | Protection against phalloidin hepatotoxicity by oleanolic acid involves activation of Nrf2 and suppression of Oatp1b2. | 25280775 |
| Type | IDs |
|---|---|
| Synonymous | 7330442B20Rik, OATP-C, OATP2, Oatp1b2, Oatp4, Slc21a10, Slc21a6, lst-1, mlst-1 |
| Gene |
UniProtKB-ID:
SO1B2_MOUSE
UniprotKB:
Q9JJL3
UniParc:
UPI000002B325,
UPI0000023434
EMBL:
AF250912,
AB031959,
AB037202
Ensembl:
ENSMUSG00000030236
KO:
mmu:28253
|
| Nucleutide sequences |
EMBL-CDS:
BAA98050.1,
AAF74719.1,
BAB03272.1
Ensembl_TRS:
ENSMUST00000042812
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044326
RefSeq:
NP_065241.1,
XP_017177100.1,
XP_036022101.1,
XP_006507026.1
|
| Others |
UniRef100:
UniRef100_Q9JJL3
UniRef90:
UniRef90_Q9JJL3
UniRef50:
UniRef50_Q9Y6L6
UniGene:
Mm.272223
CCDS:
CCDS20678.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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