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28250 Slco1a4

28250

Slco1a4

solute carrier organic anion transporter family, member 1a4

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier organic anion transporter family, member 1a4

研究结论

Date Results Publications
2018-11-10 11:58:00 Oatp1a4 plays a major role in the hepatic accumulation of cardiac glycosides in mice. 29348124
2013-09-28 11:20:00 Oatp1a4 does not appear to mediate the hepatic uptake of bile acid, but plays an important male-predominant role in secondary bile acid metabolism. 23747753
2011-12-24 11:49:00 Oatp1a4 is more highly expressed in females than in males. Null mice showed inhibited hepatocyte transporter functions and an altered urinary metabolome. 21561886
2010-03-22 11:21:00 Results show that Oatp1a4 can mediate the brain-to-blood and blood-to-brain transport of its substrate drugs across the blood-brain barrier. 19833843
2010-01-21 00:00:00 Report critical role of PPAR-alpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced downregulation of Oatp1a4 uptake transporter in mouse liver. 18703564

名称对应

Type IDs
Synonymous AI785519, Oatp1a4, Oatp2, Slc21a5
Gene
UniProtKB-ID: SO1A4_MOUSE
UniprotKB: Q9EP96
UniParc: UPI00000271EE
EMBL: AB031814, AB043023
Ensembl: ENSMUSG00000030237
KO: mmu:28250
Nucleutide sequences
EMBL-CDS: BAB18305.1, BAB12445.1
Ensembl_TRS: ENSMUST00000032364, ENSMUST00000165990
Protein sequencees
Ensembl_PRO: ENSMUSP00000130746, ENSMUSP00000032364
RefSeq: XP_036022098.1, XP_036022097.1, NP_109612.1, XP_036022100.1, NP_001342506.1, XP_011239886.1, XP_036022099.1, XP_011239887.1, XP_036022096.1
Others
UniRef100: UniRef100_Q9EP96
UniRef90: UniRef90_Q9EP96
UniRef50: UniRef50_P70502
UniGene: Mm.255586
CCDS: CCDS39690.1

全选

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