| Type | Description |
|---|---|
| Definition | solute carrier organic anion transporter family, member 1a1 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-20 11:49:00 | Organic anion-transporting polypeptides exert strong impact on disposition and toxicity of antitumor drugs. (Review) | 27449599 |
| 2017-05-13 17:04:00 | important roles for OATP1A/1B in transporter-mediated uptake and disposition of doxorubicin, are reported. | 27777271 |
| 2015-02-21 10:50:00 | Data indicate that organic anion-transporting polypeptides Oatp1a/1b-null mice had increased levels of carboxylesterase (Ces) enzymes, which caused higher conversion of irinotecan to SN-38 in plasma, potentially complicating pharmacokinetic analyses. | 24194565 |
| 2014-08-16 11:51:00 | PDZK1 regulates intracellular trafficking of Oatp1a1. | 24115750 |
| 2012-09-29 11:04:00 | Loss of Oatp1a1 function exacerbates cholestatic liver injury in mice and suggest that Oatp1a1 plays a unique role in liver adaptive responses to obstructive cholestasis. | 22461449 |
| Type | IDs |
|---|---|
| Synonymous | A530084B21, OATP-1, Oatp1, Oatp1a1, Slc21a1 |
| Gene |
UniProtKB-ID:
SO1A1_MOUSE,
Q53ZW9_MOUSE
UniprotKB:
Q9QXZ6,
Q53ZW9
UniParc:
UPI0000006C3F
EMBL:
AB031813,
AY195868,
AF223067,
BC041147,
AF148218,
AY243579
Ensembl:
ENSMUSG00000041698
KO:
mmu:28248
|
| Nucleutide sequences |
EMBL-CDS:
BAB12444.1,
AAF31457.1,
AAF19351.1,
AAH41147.1,
AAO45089.1,
AAP42199.1
Ensembl_TRS:
ENSMUST00000042119
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037022
RefSeq:
NP_038825.1
|
| Others |
UniRef100:
UniRef100_Q9QXZ6
UniRef90:
UniRef90_Q9QXZ6
UniRef50:
UniRef50_P70502
UniGene:
Mm.103665
CCDS:
CCDS39691.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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