| Type | Description |
|---|---|
| Definition | RAB guanine nucleotide exchange factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2012-10-27 11:20:00 | these data suggest differential physiological roles of the two ubiquitin binding domains in Rabex-5. | 22705550 |
| 2010-01-21 00:00:00 | The structure of the N-terminal portion of Rabex-5 bound to ubiquitin at 2.5-A resolution shows that Rabex-5-ubiquitin interactions occur at two sites | 16462746 |
| 2010-01-21 00:00:00 | Data show that ubiquitin binding is essential for the recruitment of Rabex-5 from the cytosol to endosomes, independently of its guanine nucleotide exchange factor activity and of Rab5. | 18772883 |
| 2010-01-21 00:00:00 | Rabex-5 can target to early endosomes via the EET domain and activate Rab5 in a Rabaptin-5-independent manner in vivo. | 17699593 |
| 2010-01-21 00:00:00 | Receptor recycling is mediated by AP-1/clathrin-coated vesicles and regulated by rab4 and rabaptin-5/rabex-5. | 15331762 |
| Type | IDs |
|---|---|
| Synonymous | RABEX5 |
| Gene |
UniProtKB-ID:
RABX5_BOVIN
UniprotKB:
O18973
UniParc:
UPI0000086802
EMBL:
AJ001119
KO:
bta:282335
|
| Nucleutide sequences |
EMBL-CDS:
CAA04545.1
|
| Protein sequencees |
RefSeq:
NP_777016.1
|
| Others |
UniRef100:
UniRef100_O18973
UniRef90:
UniRef90_O18973
UniRef50:
UniRef50_O18973
UniGene:
Bt.317
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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