IGFBP2 - insulin like growth factor binding protein 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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282260 IGFBP2

基因描述

Type	Description
Definition	insulin like growth factor binding protein 2

研究结论

Date	Results	Publications
2012-08-18 10:43:00	Five novel SNPs were identified in IGFBP2, two of which had significant associations with fertility (age at conception in heifers and commencement of luteal activity) and 305-day milk yield in lactation 1.	22537059
2012-03-03 11:15:00	The present study suggests that the insulin like growth factor (IGF) system or imbalances between IGF and IGF binding proteins may be involved in cystic ovary disease of cattle.	21940120
2010-01-21 00:00:00	spatial and temporal patterns of expression of IGFBP-2 and -3 were markedly altered in the placentomes of nuclear transfer pregnancies	14561651
2010-01-21 00:00:00	in preovulatory follicles, PAPP-A is responsible for IGF-dependent IGFBP-2 degradation	12493698

名称对应

Type	IDs
Gene	UniProtKB-ID: IBP2_BOVIN UniprotKB: P13384 UniParc: UPI0000087DC8 EMBL: AF074854 Ensembl: ENSBTAG00000005596 KO: bta:282260
Nucleutide sequences	EMBL-CDS: AAD04862.1 Ensembl_TRS: ENSBTAT00000007349
Protein sequencees	Ensembl_PRO: ENSBTAP00000007349 RefSeq: NP_776980.1
Others	UniRef100: UniRef100_P13384 UniRef90: UniRef90_P13384 UniRef50: UniRef50_P13384 UniGene: Bt.149

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
25319346	Periconceptional undernutrition modifies endocrine profiles and hepatic gene expression in sheep. J Anim Physiol Anim Nutr (Berl) V de Brun , A Meikle , A Casal , M Sequeira , I Contreras-SolÃs , M Carriquiry , F Forcada , C Sosa , J A Abecia	2015-08-01	GHR, IGF1R, IGFBP1, IGFBP2, ADIPOR2, ADIPOR1, RPL19, IGFBP5, LEPR, IGF1, IGF2, LEP
22537059	Associations between bovine IGFBP2 polymorphisms with fertility, milk production, and metabolic status in UK dairy cows. Anim. Biotechnol. A M Clempson , G E Pollott , J S Brickell , D C Wathes	2012-04-01	IGFBP2
21940120	Influence of insulin-like growth factor-binding proteins-2 and -3 in the pathogenesis of cystic ovarian disease in cattle. Anim. Reprod. Sci. Fernanda M RodrÃguez , Natalia R Salvetti , Carolina G Panzani , Claudio G Barbeito , Hugo H Ortega , Florencia Rey	2011-10-01	IGFBP2, IGFBP3
19393038	A whole-genome assembly of the domestic cow, Bos taurus. Genome Biol Aleksey V Zimin , Arthur L Delcher , Liliana Florea , David R Kelley , Michael C Schatz , Daniela Puiu , Finnian Hanrahan , Geo Pertea , Curtis P Van Tassell , Tad S Sonstegard , Guillaume MarÃ§ais , Michael Roberts , Poorani Subramanian , James A Yorke , Steven L Salzberg	2009-01-01	-
15129009	Insulin increases 17 beta-estradiol production by the dominant follicle of the first postpartum follicle wave in dairy cows. Reproduction S T Butler , S H Pelton , W R Butler	2004-05-01	INS, LHB, IGF1, IGFBP2, IGFBP3
14561651	Insulin-like growth factor-I and binding proteins 1, 2, and 3 in bovine nuclear transfer pregnancies. Biol. Reprod. Susan R Ravelich , Bernhard H Breier , Shiva Reddy , Jeffrey A Keelan , David N Wells , A James Peterson , Rita S F Lee	2004-02-01	IGF1, IGFBP1, IGFBP2, IGFBP3
12493698	Pregnancy-associated plasma protein-A is involved in insulin-like growth factor binding protein-2 (IGFBP-2) proteolytic degradation in bovine and porcine preovulatory follicles: identification of cleavage site and characterization of IGFBP-2 degradation. Biol. Reprod. Philippe Monget , Sabine Mazerbourg , Thierry Delpuech , Marie-Christine Maurel , SÃ©bastien ManiÃ¨re , JÃ¼rgen Zapf , Gilles Lalmanach , Claus Oxvig , Michael T Overgaard	2003-01-01	-
9677398	Alanine screening mutagenesis establishes tyrosine 60 of bovine insulin-like growth factor binding protein-2 as a determinant of insulin-like growth factor binding. J Biol Chem G D Hobba , A LÃ¶thgren , E Holmberg , B E Forbes , G L Francis , J C Wallace	1998-07-31	-
9361208	The role of insulin in the regulation of milk protein synthesis in dairy cows. J. Dairy Sci. J M Griinari , M A McGuire , D A Dwyer , D E Bauman , D M Barbano , W A House	1997-10-01	INS, IGF1, IGF2, IGFBP2
1377702	Cloning and sequence determination of bovine insulin-like growth factor binding protein-2 (IGFBP-2): comparison of its structural and functional properties with IGFBP-1. J. Cell. Biochem. M J Bourner , W H Busby , N R Siegel , G G Krivi , R H McCusker , D R Clemmons	1992-02-01	IGFBP2

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