PDE1A - phosphodiesterase 1A-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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281969 PDE1A

基因描述

Type	Description
Definition	phosphodiesterase 1A

研究结论

Date	Results	Publications
2016-10-29 11:28:00	The original finding was the identification and purification of a vinpocetine and muscarinic antagonist-inhibited and CaM-activated plasma membrane-bound PDE1A, linked to M(2)AChR.	26513204
2010-01-21 00:00:00	analysis of calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1) splice variants from bovine cardiac muscle	17467927
2010-01-21 00:00:00	Although cAMP regulation by PDE 1 may occur early during capacitation, downstream events appear to prevent full capacitation from occurring prematurely.	12514091

名称对应

Type	IDs
Synonymous	PDE1
Gene	UniProtKB-ID: PDE1A_BOVIN UniprotKB: P14100 UniParc: UPI0000144B4D, UPI000002A6C0 EMBL: BC123449, M90358, L34069 Ensembl: ENSBTAG00000012100 KO: bta:281969
Nucleutide sequences	EMBL-CDS: AAI23450.1, AAA92555.1, AAA74560.1 Ensembl_TRS: ENSBTAT00000016060, ENSBTAT00000052318
Protein sequencees	Ensembl_PRO: ENSBTAP00000016060, ENSBTAP00000051204 RefSeq: XP_024854622.1, XP_010800146.1, XP_010800149.2, XP_015330124.1, XP_010800145.2, XP_005202314.3, XP_010800147.1, XP_024854603.1, XP_010800148.1, XP_010800144.2, XP_024854627.1, NP_776839.1
Others	UniRef100: UniRef100_P14100 UniRef90: UniRef90_P14100 UniRef50: UniRef50_P54750 UniGene: Bt.512

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
26513204	A novel PDE1A coupled to M2AChR at plasma membranes from bovine tracheal smooth muscle. J. Recept. Signal Transduct. Res. Patrizzia Mastromatteo-Alberga , Fabiola Placeres-Uray , Marcelo A Alfonzo-GonzÃ¡lez , Ramona Gonzalez de Alfonzo , Itala Lippo de Becemberg , Marcelo J Alfonzo	2016-01-01	-
19393038	A whole-genome assembly of the domestic cow, Bos taurus. Genome Biol Aleksey V Zimin , Arthur L Delcher , Liliana Florea , David R Kelley , Michael C Schatz , Daniela Puiu , Finnian Hanrahan , Geo Pertea , Curtis P Van Tassell , Tad S Sonstegard , Guillaume MarÃ§ais , Michael Roberts , Poorani Subramanian , James A Yorke , Steven L Salzberg	2009-01-01	-
17467927	Calmodulin-dependent cyclic nucleotide phosphodiesterase (PDE1) splice variants from bovine cardiac muscle. Gene Shankar B Das , Chris Dinh , Sachin Shah , Doug Olson , Andrew Ross , Ponniah Selvakumar , Rajendra K Sharma	2007-07-15	PDE1A
16470652	Analysis of the interacting partners of the neuronal calcium-binding proteins L-CaBP1, hippocalcin, NCS-1 and neurocalcin delta. Proteomics Lee P Haynes , Daniel J Fitzgerald , Brian Wareing , Dermott W O'Callaghan , Alan Morgan , Robert D Burgoyne	2006-03-01	Hpca, Ncs1, CABP1, CNP, NCALD, PDE1A, ARF1
8537356	Identification of inhibitory and calmodulin-binding domains of the PDE1A1 and PDE1A2 calmodulin-stimulated cyclic nucleotide phosphodiesterases. J Biol Chem W K Sonnenburg , D Seger , K S Kwak , J Huang , H Charbonneau , J A Beavo	1995-12-29	-
7568196	Molecular cloning and characterization of a calmodulin-dependent phosphodiesterase enriched in olfactory sensory neurons. Proc. Natl. Acad. Sci. U.S.A. C Yan , A Z Zhao , J K Bentley , K Loughney , K Ferguson , J A Beavo	1995-10-10	-
7678006	Molecular cloning of a cDNA encoding the "61-kDa" calmodulin-stimulated cyclic nucleotide phosphodiesterase. Tissue-specific expression of structurally related isoforms. J Biol Chem W K Sonnenburg , D Seger , J A Beavo	1993-01-05	-
1651111	Evidence for domain organization within the 61-kDa calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine brain. Biochemistry H Charbonneau , S Kumar , J P Novack , D K Blumenthal , P R Griffin , J Shabanowitz , D F Hunt , J A Beavo , K A Walsh	1991-08-13	-
3025833	Identification of a conserved domain among cyclic nucleotide phosphodiesterases from diverse species. Proc. Natl. Acad. Sci. U.S.A. H Charbonneau , N Beier , K A Walsh , J A Beavo	1986-12-01	-
6667031	Dictyostelium calmodulin: affinity isolation and characterization. Arch. Biochem. Biophys. G A Jamieson , W A Frazier	1983-12-01	-

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