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281894 LALBA

281894

LALBA

lactalbumin alpha

protein-coding

Bos taurus

基因描述

Type Description
Definition lactalbumin alpha

研究结论

Date Results Publications
2017-12-02 11:52:00 This study shows, for the first time, that alpha-lactalbumin isolated in a rare 28kDa dimeric form induces cell death, while 14kDa monomeric alpha-lactalbumin is inactive. 28193539
2015-12-26 11:47:00 Macromolecular crowding reduces the calcium binding affinity of holo-lactalbumin alpha resulting in the formation of apo-lactalbumin alpha (the calcium-depleted form of holo-LA) leading to aggregate formation. 25437004
2015-09-05 11:09:00 Data suggest that stabilization of apo-alpha-lactalbumin by mono- and oligo-saccharides can be accounted for by simplified statistical-thermodynamic model considering volume exclusion deriving from steric repulsion between protein and saccharides. 26000826
2014-04-12 10:51:00 These findings suggest that the SNP alpha-LA2516 in the alpha-LA gene likely does not have potential as a molecular marker for milk production traits in Chinese Holstein cows. 24065678
2012-11-24 10:16:00 alphaLA forms a misfolded disulfide bond shuffled isomer, X-alphaLA which represents a different low energy fold for the protein; binding calcium plays an important role in both maintaining the native structure of alphaLA and providing a mechanism for distinguishing between folded and misfolded species. 22189830

名称对应

Type IDs
Synonymous a-LACTA, alfaLA
Gene
UniProtKB-ID: LALBA_BOVIN, B6V3I5_BOVIN
UniprotKB: P00711, B6V3I5
UniParc: UPI000012E267
EMBL: BC102173, AB052163, AB052167, AB052164, M18780, X06366, AB052166, FJ232912, J05147, AB052165, BT025469, M90645, AF249896
KO: bta:281894
Nucleutide sequences
EMBL-CDS: BAB18925.1, BAB18921.1, AAA30614.1, AAI02174.1, BAB18922.1, AAA30615.1, CAA29664.1, AAF63624.1, AAA30367.1, BAB18923.1, BAB18924.1, ABF57425.1, ACI62509.1
Protein sequencees
RefSeq: NP_776803.1
Others
UniRef100: UniRef100_P00711
UniRef90: UniRef90_P00711
UniRef50: UniRef50_P00711
UniGene: Bt.87412

全选

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