| Type | Description |
|---|---|
| Definition | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 10:45:00 | This study focused on the reaction of the bovine CYP17A1 enzyme with progesterone as a substrate. On the basis of a created homology model, active-site residues were identified and systematically mutated to alanine. In whole-cell biotransformations, the importance of the N202, R239, G297 and E305 residues for substrate conversion was confirmed. | 29981252 |
| 2013-07-13 12:18:00 | BMP6 has a role in downregulating INSL3 and CYP17A1 and other proteins that modulate ovarian androgen production | 23530236 |
| 2012-08-04 11:42:00 | By alignment analysis and sequencing, we detected that the g.329C>T SNP is a false positive polymorphism, which allows us to explain the inflated heterozygotic value. | 22405876 |
| 2012-05-19 11:14:00 | The binding of SF-1 to the CYP17 and StAR promoter regions increased in theca cells incubated with low levels of luteinizing hormone. | 22155568 |
| 2012-04-21 12:01:00 | Data suggest that the upstream region of gene encoding CYP17 contains unique cAMP-responsive sequence and appears to bind unique nuclear proteins or transcription factors in adrenal cortex. [REVIEW] | 22217838 |
| Type | IDs |
|---|---|
| Synonymous | CYP17, CYPXVII, P450-C17, P450c17 |
| Gene |
UniProtKB-ID:
CP17A_BOVIN
UniprotKB:
P05185
UniParc:
UPI0000128305
EMBL:
BC110169,
M12547
Ensembl:
ENSBTAG00000014335,
ENSBTAG00000054516
KO:
bta:281739
|
| Nucleutide sequences |
EMBL-CDS:
AAI10170.1,
AAA30485.1
Ensembl_TRS:
ENSBTAT00000087082,
ENSBTAT00000019061
|
| Protein sequencees |
Ensembl_PRO:
ENSBTAP00000069265,
ENSBTAP00000019061
RefSeq:
NP_776729.1,
XP_024841233.1,
XP_024841234.1
|
| Others |
UniRef100:
UniRef100_P05185
UniRef90:
UniRef90_P05185
UniRef50:
UniRef50_P19100
UniGene:
Bt.89153
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| 1 |
University of Texas Southwestern Medical Center |
3 |
| 2 |
Institute for Physical Science and Technology |
1 |
| 3 |
University of Reading |
1 |
| 4 |
INSERM U 244 Centre d'Etudes Nucléaires, Grenoble, France. |
1 |
| 5 |
Obihiro University of Agriculture and Veterinary Medicine |
1 |
| 排名 | 研究人员 | 文献 |
|---|---|---|
| 1 |
M R Waterman |
4 |
| 2 |
E R Simpson |
3 |
| 3 |
M X Zuber |
2 |
| 4 |
M E John |
2 |
| 5 |
Jens Vanselow |
2 |