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2817 GPC1

2817

GPC1

glypican 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition glypican 1

研究结论

Date Results Publications
2021-02-27 13:49:00 Association of common variation in ADD3 and GPC1 with biliary atresia susceptibility. 32315284
2020-12-26 13:13:00 Anti-glypican-1 antibody-drug conjugate is a potential therapy against pancreatic cancer. 32152502
2020-10-31 13:14:00 Paradoxical Role of Glypican-1 in Prostate and Tumor Growth. 31391540
2020-04-25 10:24:00 Highly (SN12L1) and low (SN12C) metastatic renal carcinoma cell line were analyzed. There was significant elevation of Glypican-1 protein expression in the SN12L1 cells relative to the SN12C cells while there were no significant differences in Syndecan-1 or CD44. Knock down of Glypican-1 by siRNA completely blocked flow induced migration in SN12L1 cells. MAPK inhibitors also blocked flow induced migration in SN12L1 cells. 31256115
2020-03-14 12:23:00 expression significantly reduced in first-trimester small for gestational age as well as in the third-trimester fetal growth restriction placentae compared to controls 30803713

名称对应

Type IDs
Synonymous glypican
Gene
UniProtKB-ID: GPC1_HUMAN, H7C410_HUMAN, A0A384NPH9_HUMAN
UniprotKB: P35052, H7C410, A0A384NPH9
UniParc: UPI0000209831, UPI000013D4AA, UPI0000140648
EMBL: AK095397, AK096638, BC051279, GQ891296, CH471063, X54232, AC110619
Ensembl: ENSG00000063660
KO: hsa:2817
Nucleutide sequences
EMBL-CDS: AAH51279.1, EAW71180.1, BAG53345.1, AAY24160.1, CAA38139.1, EAW71183.1, BAG53043.1, ADO22158.1
Ensembl_TRS: ENST00000264039, ENST00000420138
Protein sequencees
Ensembl_PRO: ENSP00000264039, ENSP00000415077
RefSeq: NP_002072.2, XP_011509278.1
Others
UniRef100: UniRef100_P35052
UniRef90: UniRef90_P35052
UniRef50: UniRef50_P35052
UniGene: Hs.328232
CCDS: CCDS2534.1

全选

研究热度
发表文献
研究结论
热点单位
排名 科研单位 文献
1

Lund University

7
2

University of California

5
3

The University of Texas MD Anderson Cancer Center

2
4

University of British Columbia

2
5

King's College London

2
热点人员
排名 研究人员 文献
1

Katrin Mani

7
2

Murray Korc

4
3

G David

4
4

A D Lander

3
5

Lars-Ake Fransson

3
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