| Type | Description |
|---|---|
| Definition | serpin family E member 1 |
| Date | Results | Publications |
|---|---|---|
| 2016-12-24 11:40:00 | Data show that urokinase-type plasminogen activator (uPA) is only expressed in the cumulus cells of immature and in vitro matured cumulus-oocyte complexes (COCs), while uPA receptor (uPAR) and plasminogen activator inhibitor-1 (PAI-1) are expressed in both the cumulus cells and the immature and in vitro matured oocytes. | 25939353 |
| 2011-09-24 11:49:00 | Data suggest PAI1 plays key role in modulating chromaffin cell neurosecretory function. Evidence is presented that in chromaffin cells, PAI1 is targeted to storage vesicles and co-released with catecholamine upon secretagogue/stress stimulation. | 21596853 |
| 2010-01-21 00:00:00 | the PI3K/Akt pathway acts as a negative regulator of PAI-1 expression in vascular endothelial cells, in part, through the downregulation of MAPK pathways | 17172275 |
| 2010-01-21 00:00:00 | FoxO1 inhibits PAI-1 expression through the inhibition of TGF-beta/Smad-mediated signaling pathways. | 19563779 |
| 2010-01-21 00:00:00 | high glucose-induced plasminogen activator inhibitor-1 (PAI-1) expression in endothelial cells is mediated by NF-kappaB activation through the Rho/Rho-kinase pathway | 17275007 |
| Type | IDs |
|---|---|
| Synonymous | PAI1 |
| Gene |
UniProtKB-ID:
PAI1_BOVIN,
A0A0M5L1T6_BOVIN
UniprotKB:
P13909,
A0A0M5L1T6
UniParc:
UPI000002FBA6
EMBL:
BC103451,
BT025406,
X52906,
X16383,
KR006346
KO:
bta:281375
|
| Nucleutide sequences |
EMBL-CDS:
ABF57362.1,
AAI03452.1,
CAA34419.1,
CAA37094.1,
ALE14677.1
|
| Protein sequencees |
RefSeq:
XP_010817781.1,
NP_776562.1,
XP_024840412.1
|
| Others |
UniRef100:
UniRef100_P13909
UniRef90:
UniRef90_P13909
UniRef50:
UniRef50_P13909
UniGene:
Bt.5229
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 25939353 |
Zygote Daniela C GarcÃa , Dora C Miceli , Gabriela Rizo , Elina V GarcÃa , Pablo A Valdecantos , Mariela Roldán-Olarte |
2016-04-01 | - |
| 21596853 |
Blood Qijiao Jiang , Neill A Gingles , Marc A Olivier , Lindsey A Miles , Robert J Parmer |
2011-06-30 | - |
| 19563779 |
Biochem. Biophys. Res. Commun. Yun-A Jung , Kyeong-Min Lee , Mi-Kyung Kim , Gwon-Soo Jung , Ye-Jin Seo , Hye-Soon Kim , Ho-Chan Cho , Ki-Up Lee , Keun-Gyu Park , In-Kyu Lee |
2009-09-04 |
FOXO1,
SERPINE1
|
| 19393038 |
A whole-genome assembly of the domestic cow, Bos taurus. Genome Biol Aleksey V Zimin , Arthur L Delcher , Liliana Florea , David R Kelley , Michael C Schatz , Daniela Puiu , Finnian Hanrahan , Geo Pertea , Curtis P Van Tassell , Tad S Sonstegard , Guillaume Marçais , Michael Roberts , Poorani Subramanian , James A Yorke , Steven L Salzberg |
2009-01-01 | - |
| 17275007 |
Atherosclerosis Hitoshi Iwasaki , Ryuji Okamoto , Shinya Kato , Katsuhisa Konishi , Hideo Mizutani , Norikazu Yamada , Naoki Isaka , Takeshi Nakano , Masaaki Ito |
2008-01-01 |
SERPINE1
|
| 17172275 |
Am J Physiol Heart Circ Physiol Yasushi Mukai , Chao-Yung Wang , Yoshiyuki Rikitake , James K Liao |
2007-04-01 | - |
| 16305752 |
Characterization of 954 bovine full-CDS cDNA sequences. BMC Genomics Gregory P Harhay , Tad S Sonstegard , John W Keele , Michael P Heaton , Michael L Clawson , Warren M Snelling , Ralph T Wiedmann , Curt P Van Tassell , Timothy P L Smith |
2005-01-01 |
STK24,
UBAP2L,
ERCC2,
BTNL9,
ATRAID,
JMJD7,
LRWD1,
GPSM1,
RAD54L,
MKS1,
CCBL1,
FAM161B,
LOC107131293,
SERPINA1,
AK1,
AK2,
BGN,
CEL,
CLU,
DBH,
DCN,
DDC,
FOS,
NPC2,
LEP,
MOG,
OGN,
ST7,
TST,
ZP3,
ACTB,
PLIN2,
AOC3,
APOE,
ARNT,
CGN1,
COX4I1,
CTSV,
ECE1,
S1PR1,
FDX1,
FMOD,
FSHR,
FUT1,
GNB1,
GOT1,
HPRT1,
F11R,
LDHB,
M6PR,
MAOA,
MCM3,
MDH2,
MSRA,
NCF1,
NT5E,
OLR1,
P4HB,
SERPINE1,
PLAU,
PLOD1,
PON2,
PPIB,
PSAP,
SDHA,
SOD2,
SPP1,
TCN2,
TPI1,
VIL1,
WASL,
ACTG2,
ALDH1A1,
ANXA4,
ANXA5,
ANXA8L1,
BCAT2,
BLCAP,
C4BPA,
CCNB2,
CCNG1,
ACKR4,
DNAJC14,
COPZ1,
CPSF3,
CREB1,
CREB3,
CTBP2,
ECHS1,
EDNRA,
FABP3,
FABP5,
HADHB,
HSPA2,
HSPA8,
HYAL2,
IKBKB,
IKBKG,
IMPA1
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 11282978 |
Genome Res. T P Smith , W M Grosse , B A Freking , A J Roberts , R T Stone , E Casas , J E Wray , J White , J Cho , S C Fahrenkrug , G L Bennett , M P Heaton , W W Laegreid , G A Rohrer , C G Chitko-McKown , G Pertea , I Holt , S Karamycheva , F Liang , J Quackenbush , J W Keele |
2001-04-01 |
UBAP2L,
ERCC2,
BTNL9,
SSLP1,
C29H11orf68,
PHRF1,
GTF3A,
JMJD7,
SETDB1,
LRWD1,
GPSM1,
RAD54L,
STON1,
C15H11orf96,
C5H12orf75,
MAP2K5,
IFNT3,
IFNT,
LOC100335806,
AOC2,
LOC100848357,
LOC100848895,
SLX4IP,
NUS1,
MKS1,
MEG9,
FAM161B,
LOC107131293,
SERPINA1,
AK1,
AK2,
BGN,
CEL,
DBH,
DDC,
FOS,
HCK,
LEP,
MOG,
PLG,
REN,
ST7,
ZP3,
ACTB,
AOC3,
ARNT,
CGN1,
ECE1,
ECE2,
S1PR1,
FSHR,
FUT1,
GOT1,
HPRT1,
F11R,
MCM3,
NCF1,
DHRS4,
NT5E,
OLR1,
SERPINE1,
PLOD1,
PSAP,
RCN1,
PMEL,
TCN2,
VIL1,
WASL,
ABCF1,
ANXA4,
ANXA8L1,
BCAT2,
BFSP1,
CCNB2,
CCNG1,
ACKR4,
DNAJC14,
COPZ1,
CPSF3,
CREB1,
CREB3,
EDNRA,
TRMT2A,
HYAL2,
IKBKB,
IKBKG,
ITPR3,
LALBA,
MMP14,
MOCS1,
NCALD,
NCAM1,
OPCML,
OVGP1,
POLD2,
PPARA,
PSMD4,
SARS2,
TOP2B
|
| 8186264 |
Biochim. Biophys. Acta C W Heegaard , L K Rasmussen , P A Andreasen |
1994-05-26 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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