| Type | Description |
|---|---|
| Definition | endothelin 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-06-24 11:23:00 | EDN-1 may be involved in the protection of sperm from phagocytosis by polymorphonuclear neutrophils in the bovine oviduct, supporting sperm survival until fertilization | 26781611 |
| 2017-04-08 11:46:00 | Data suggest that, in Fallopian tubes, endothelins (EDN1, EDN2, EDN3) and EDN-converting enzymes (ECE1, ECE2) are expressed in epithelial cells; EDN receptors (EDNRA, EDNRB) are present in smooth-muscle. Expression of EDN1, EDN2, and ECE2 is highest on day of ovulation. EDN/ENDR signaling appears to participate Fallopian tube function. These studies were conducted in Holstein cows. | 25370848 |
| 2017-02-18 11:39:00 | results suggest that ET-1-induced activation of proMMP-2 is mediated via cross-talk between NADPH and NFkappaB-MT1MMP signaling pathways along with a marked decrease in TIMP-2 expression in the cells | 26910780 |
| 2015-09-26 19:56:00 | We demonstrated that (i) treatment of bovine pulmonary artery smooth muscle cells with ET-1 stimulates cPLA2 activity in the cell membrane. | 25399298 |
| 2013-03-09 11:26:00 | Differential cell-specific and spatiotemporal expression of the EDN1 system and NOS in the bovine utero-placental unit may be associated with regulation of vascular and cellular functions during pregnancy. | 22921266 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
EDN1_BOVIN
UniprotKB:
P17322
UniParc:
UPI000012A214
EMBL:
BC102459,
X52740,
X52942,
S37093
Ensembl:
ENSBTAG00000008096
KO:
bta:281137
|
| Nucleutide sequences |
EMBL-CDS:
AAB22241.1,
CAA36954.1,
CAA37117.1,
AAI02460.1
Ensembl_TRS:
ENSBTAT00000010649
|
| Protein sequencees |
Ensembl_PRO:
ENSBTAP00000010649
RefSeq:
NP_851353.1
|
| Others |
UniRef100:
UniRef100_P17322
UniRef90:
UniRef90_P17322
UniRef50:
UniRef50_P05305
UniGene:
Bt.59529
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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