MTTP - microsomal triglyceride transfer protein-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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280868 MTTP

基因描述

Type	Description
Definition	microsomal triglyceride transfer protein

研究结论

Date	Results	Publications
2015-11-28 10:45:00	Nonesterified fatty acids significantly inhibit the expression of ApoB100, ApoE, MTP, and LDLR, thereby decreasing the synthesis and assembly of VLDL and inducing TG accumulation in bovine hepatocytes.	24377799
2010-01-21 00:00:00	measurements of the transfer of phospholipids (PLs) and cholesteryl esters (CEs)to acceptor vesicles by purified MTP showed TAG transfer activity was the most robust, and CE and PL transfer activities were 60-71% and 5-13% of the TAG transfer activity	15897609
2010-01-21 00:00:00	after calving the apolipoprotein B(100) mRNA synthesis was lower, whereas microsomal triglyceride transfer protein (MTP) and apolipoprotein E messenger RNA abundance were higher in the liver	15375048

名称对应

Type	IDs
Synonymous	MTP
Gene	UniProtKB-ID: A7MBC6_BOVIN UniprotKB: A7MBC6 UniParc: UPI00015AA679 EMBL: BC151485 KO: bta:280868
Nucleutide sequences	EMBL-CDS: AAI51486.1
Protein sequencees	RefSeq: NP_001095304.1
Others	UniRef100: UniRef100_A7MBC6 UniRef90: UniRef90_P55156 UniRef50: UniRef50_O08601 UniGene: Bt.64166

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mRNA

Protein

UniprotKB

Description

Refseq

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Location

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Pubmed编号	文献信息	发表日期	相关基因
24377799	Effects of nonesterified fatty acids on the synthesis and assembly of very low density lipoprotein in bovine hepatocytes in vitro. J. Dairy Sci. Lei Liu , Xinwei Li , Yu Li , Yuan Guan , Yuxiang Song , Liheng Yin , Hui Chen , Liancheng Lei , Juxiong Liu , Xiaobing Li , Zhe Wang , Xiaoyu Yang , Guowen Liu	2014-03-01	MTTP, APOE, LDLR, APOB
19393038	A whole-genome assembly of the domestic cow, Bos taurus. Genome Biol Aleksey V Zimin , Arthur L Delcher , Liliana Florea , David R Kelley , Michael C Schatz , Daniela Puiu , Finnian Hanrahan , Geo Pertea , Curtis P Van Tassell , Tad S Sonstegard , Guillaume MarÃ§ais , Michael Roberts , Poorani Subramanian , James A Yorke , Steven L Salzberg	2009-01-01	-
15897609	Transfer of cholesteryl esters and phospholipids as well as net deposition by microsomal triglyceride transfer protein. J Lipid Res Paul Rava , Humra Athar , Caroline Johnson , M Mahmood Hussain	2005-08-01	-
15375048	Abundance of mRNA of apolipoprotein b100, apolipoprotein e, and microsomal triglyceride transfer protein in liver from periparturient dairy cows. J. Dairy Sci. U Bernabucci , B Ronchi , L BasiricÃ² , D Pirazzi , F Rueca , N Lacetera , A Nardone	2004-09-01	MTTP, APOE, APOB
8876250	An inhibitor of the microsomal triglyceride transfer protein inhibits apoB secretion from HepG2 cells. Proc. Natl. Acad. Sci. U.S.A. H Jamil , D A Gordon , D C Eustice , C M Brooks , J K Dickson , Y Chen , B Ricci , C H Chu , T W Harrity , C P Ciosek , S A Biller , R E Gregg , J R Wetterau	1996-10-15	-
8361539	Cloning and gene defects in microsomal triglyceride transfer protein associated with abetalipoproteinaemia. Nature D Sharp , L Blinderman , K A Combs , B Kienzle , B Ricci , K Wager-Smith , C M Gil , C W Turck , M E Bouma , D J Rader	1993-09-02	MTTP, MTTP
2351674	Protein disulfide isomerase is a component of the microsomal triglyceride transfer protein complex. J Biol Chem J R Wetterau , K A Combs , S N Spinner , B J Joiner	1990-06-15	-

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