| Type | Description |
|---|---|
| Definition | proteoglycan 4 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-14 11:40:00 | TGF-beta1 stimulated lubricin secretion by superficial zone chondrocytes at all densities with twice-a-week TGF-beta treatment. It is noteworthy that the daily treatment of TGF-beta1 increased lubricin much higher compared with twice-a-week treatment. | 28578597 |
| 2016-12-17 11:14:00 | the intermolecular disulfide-bonded multimeric structure of PRG4 is important for its ability to adsorb to a cartilage surface and function as a boundary lubricant. | 26631309 |
| 2016-11-05 10:19:00 | The present investigation provides novel insights into the role of the Wnt signalling pathways in SZP accumulation in synoviocytes and their roles in the homeostasis of normal joints. | 23955850 |
| 2016-06-04 11:44:00 | The important role of PRG4 in reducing friction in the tissues and compartments of the knee/stifle joint. | 26117076 |
| 2016-04-09 11:25:00 | The role of cell surface glycosaminoglycans (GAGs) during TGF-beta1 stimulation of SZP/lubricin/PRG4 in superficial zone articular chondrocytes, was investigated. | 25398329 |
| Type | IDs |
|---|---|
| Synonymous | MSF, lubricin |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees |
RefSeq:
XP_024831762.1,
XP_024831766.1,
XP_024831764.1,
XP_024831763.1,
NP_001193562.1
|
| Others |
UniGene:
Bt.62170
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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