| Type | Description |
|---|---|
| Definition | selenoprotein H |
| Date | Results | Publications |
|---|---|---|
| 2019-09-28 12:45:00 | The high levels of SELENOH in tumors as well as in undifferentiated, proliferative cells together with its inhibitory effects on proliferation and G1/S phase transition suggest SELENOH as a key regulator for cell cycle progression and for prevention of uncontrolled proliferation | 29330096 |
| 2019-02-02 12:33:00 | the obtained results clearly illustrate Sec residue plays an important role to restore functionally active conformation of SELENOH. The present study broadened our current understanding regarding the role of selenocysteine in protein structure and function. | 29480333 |
| 2018-01-27 12:08:00 | Transcriptome analysis revealed that SepH deficiency induces an inflammatory response and activates the p53 pathway. Consequently, loss of seph renders larvae susceptible to oxidative stress and DNA damage. Finally, we demonstrate that seph interacts with p53 deficiency in adulthood to accelerate gastrointestinal tumor development | 27588899 |
| 2015-03-07 11:05:00 | Selenoprotein H suppresses cellular senescence through genome maintenance and redox regulation. | 25336634 |
| 2013-09-14 10:42:00 | We conclude that the effects of selenoprotein H on mitochondrial biogenesis and mitochondrial function are probably mediated through protein kinase A-CREB-PGC-1alpha and Akt/protein kinase B-CREB-PGC-1alpha pathways. | 23220172 |
| Type | IDs |
|---|---|
| Synonymous | C11orf31, C17orf10, SELH |
| Gene |
UniProtKB-ID:
SELH_HUMAN
UniprotKB:
Q8IZQ5
UniParc:
UPI0000163E14
EMBL:
BC021122,
AF536829
Ensembl:
ENSG00000211450
KO:
hsa:280636
|
| Nucleutide sequences |
EMBL-CDS:
AAH21122.2,
AAN61472.1
Ensembl_TRS:
ENST00000534355,
ENST00000388857
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000434511,
ENSP00000373509
RefSeq:
NP_001308264.1,
NP_734467.1
|
| Others |
UniRef100:
UniRef100_Q8IZQ5
UniRef90:
UniRef90_Q8IZQ5
UniRef50:
UniRef50_Q8IZQ5
UniGene:
Hs.655373
CCDS:
CCDS44602.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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