Type | Description |
---|---|
Definition | EF hand domain containing 2 |
Date | Results | Publications |
---|---|---|
2021-02-20 13:32:00 | Swiprosin-1/EFhD-2 Expression in Cardiac Remodeling and Post-Infarct Repair: Effect of Ischemic Conditioning. | 32397496 |
2019-11-02 12:50:00 | Study in LPS-induced or cecal ligation and puncture-induced sepsis in mice report that swiprosin-1 (also known as EFhd2) plays an important role in the macrophage immune response to sepsis in mice. Swiprosin-1 depletion causes higher mortality, more severe organ dysfunction, restrained macrophage recruitment in the lung and kidney, and attenuated inflammatory cytokine production. | 29415882 |
2019-07-20 12:59:00 | EFHD2 is an important regulator of T cell cytotoxicity and further studies should evaluate its role in T cell-mediated inflammation | 30275048 |
2019-01-19 10:03:00 | Together with our finding of severe hippocampal tauopathy in Efhd2 knockout mice, these data connect Efhd2 to impaired synaptic plasticity as present in Alzheimer's disease and identify a role of Efhd2 in neuronal survival and synaptic integration in the adult hippocampus | 29337116 |
2018-10-20 11:20:00 | These results indicate that swiprosin-1 in the vestibular nuclei is a critical determinant of the susceptibility to motion sickness. | 28128226 |
Type | IDs |
---|---|
Synonymous | 2600015J22Rik, AA408606, D4Wsu27e |
Gene |
UniProtKB-ID:
Q8C845_MOUSE
UniprotKB:
Q8C845
UniParc:
UPI00000E9924
EMBL:
AL645731,
AK150207,
AK159367,
AK048475,
AK167267,
AK169409,
BC125303
Ensembl:
ENSMUSG00000040659
KO:
mmu:27984
|
Nucleutide sequences |
EMBL-CDS:
BAC33348.1,
BAE29378.1,
BAE35025.1,
AAI25304.1,
BAE41155.1,
BAE39380.1
Ensembl_TRS:
ENSMUST00000036854
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044502
RefSeq:
NP_080270.2
|
Others |
UniRef100:
UniRef100_Q8C845
UniRef90:
UniRef90_Q9D8Y0
UniRef50:
UniRef50_Q96C19
UniGene:
Mm.395598
|
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---|---|---|---|---|---|---|---|---|
Refseq |
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Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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