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27984 Efhd2

27984

Efhd2

EF hand domain containing 2

protein-coding

Mus musculus

基因描述

Type Description
Definition EF hand domain containing 2

研究结论

Date Results Publications
2021-02-20 13:32:00 Swiprosin-1/EFhD-2 Expression in Cardiac Remodeling and Post-Infarct Repair: Effect of Ischemic Conditioning. 32397496
2019-11-02 12:50:00 Study in LPS-induced or cecal ligation and puncture-induced sepsis in mice report that swiprosin-1 (also known as EFhd2) plays an important role in the macrophage immune response to sepsis in mice. Swiprosin-1 depletion causes higher mortality, more severe organ dysfunction, restrained macrophage recruitment in the lung and kidney, and attenuated inflammatory cytokine production. 29415882
2019-07-20 12:59:00 EFHD2 is an important regulator of T cell cytotoxicity and further studies should evaluate its role in T cell-mediated inflammation 30275048
2019-01-19 10:03:00 Together with our finding of severe hippocampal tauopathy in Efhd2 knockout mice, these data connect Efhd2 to impaired synaptic plasticity as present in Alzheimer's disease and identify a role of Efhd2 in neuronal survival and synaptic integration in the adult hippocampus 29337116
2018-10-20 11:20:00 These results indicate that swiprosin-1 in the vestibular nuclei is a critical determinant of the susceptibility to motion sickness. 28128226

名称对应

Type IDs
Synonymous 2600015J22Rik, AA408606, D4Wsu27e
Gene
UniProtKB-ID: Q8C845_MOUSE
UniprotKB: Q8C845
UniParc: UPI00000E9924
EMBL: AL645731, AK150207, AK159367, AK048475, AK167267, AK169409, BC125303
Ensembl: ENSMUSG00000040659
KO: mmu:27984
Nucleutide sequences
EMBL-CDS: BAC33348.1, BAE29378.1, BAE35025.1, AAI25304.1, BAE41155.1, BAE39380.1
Ensembl_TRS: ENSMUST00000036854
Protein sequencees
Ensembl_PRO: ENSMUSP00000044502
RefSeq: NP_080270.2
Others
UniRef100: UniRef100_Q8C845
UniRef90: UniRef90_Q9D8Y0
UniRef50: UniRef50_Q96C19
UniGene: Mm.395598

全选

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