| Type | Description |
|---|---|
| Definition | G protein subunit alpha o1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:08:00 | Structures of the glucocorticoid-bound adhesion receptor GPR97-Go complex. | 33408414 |
| 2020-11-21 13:19:00 | Pediatric ependymoma: GNAO1, ASAH1, IMMT and IPO7 protein expression and 5-year prognosis correlation. | 31505435 |
| 2019-10-26 11:43:00 | Gnao1+/G203R mice phenocopy children with heterozygous GNAO1 G203R mutations, showing both movement disorder and a relatively mild epilepsy pattern. This mouse model should be useful in mechanistic and preclinical studies of GNAO1-related movement disorders. | 30682176 |
| 2018-07-21 10:37:00 | first report of siblings of opposite sex harboring the same GNAO1 mutation but showing differences in phenotype with pronounced dystonia in the boy and epilepsy in his sister. | 28628939 |
| 2018-06-09 10:05:00 | GNAO1 transcription was inhibited by promoter hypermethylation, contributing to its low expression. It was further revealed that the silencing effect was regulated by methyltransferase 1 (DNMT1), and was further enhanced by transforming growth factor beta (TGF-beta). | 29709639 |
| Type | IDs |
|---|---|
| Synonymous | EIEE17, G-ALPHA-o, GNAO, HLA-DQB1, NEDIM |
| Gene |
UniProtKB-ID:
GNAO_HUMAN,
B3KP89_HUMAN,
Q6AWC5_HUMAN,
Q8N6I9_HUMAN
UniprotKB:
P09471,
B3KP89,
Q6AWC5,
Q8N6I9
UniParc:
UPI000004D206,
UPI0000401F72,
UPI00001BDAC8,
UPI000007349C,
UPI000037186B
EMBL:
Y18213,
M60163,
M19184,
M60161,
M60164,
M60159,
M19182,
M60158,
M60157,
M60162,
M60160,
AK056008,
AF493895,
BX647214,
AF493894,
BC030027,
M60156
Ensembl:
ENSG00000087258
KO:
hsa:2775
|
| Nucleutide sequences |
EMBL-CDS:
AAA52584.1,
CAB46639.1,
AAA52586.1,
AAM12608.1,
AAM12609.1,
AAA52585.1,
BAG51601.1,
CAH10548.1,
AAH30027.2
Ensembl_TRS:
ENST00000262494,
ENST00000262493,
ENST00000638705
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000491223,
ENSP00000262493,
ENSP00000262494
RefSeq:
XP_011521305.1,
NP_620073.2,
NP_066268.1
|
| Others |
UniRef100:
UniRef100_P09471,
UniRef100_P09471-2,
UniRef100_B3KP89,
UniRef100_Q8N6I9
UniRef90:
UniRef90_P59215,
UniRef90_B3KP89
UniRef50:
UniRef50_P51875,
UniRef50_P59215
UniGene:
Hs.644524
CCDS:
CCDS10757.1,
CCDS10756.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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