| Type | Description |
|---|---|
| Definition | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:33:00 | PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis. | 33097662 |
| 2018-03-31 10:42:00 | These findings identify P-Rex1 as a novel player of pulmonary fibrosis. | 27173636 |
| 2016-08-13 10:51:00 | A novel mechanism of P-Rex1 regulation through the GPCR-adaptor protein Norbin. | 26792863 |
| 2016-07-30 11:43:00 | Tiam1 and P-Rex1 promote Rac1 anti- and pro-migratory signalling cascades. | 26887924 |
| 2016-06-04 10:49:00 | findings suggest a vital role of P-Rex1 signaling in CA1 LTD that is critical for social behavior and cognitive function and offer new insight into the etiology of ASDs | 26621702 |
| Type | IDs |
|---|---|
| Synonymous | G630042G04, P-REX1, Setd6 |
| Gene |
UniProtKB-ID:
PREX1_MOUSE
UniprotKB:
Q69ZK0
UniParc:
UPI0000193496,
UPI00000EB27E
EMBL:
AK173168,
AL732357,
AK090301,
AL591884,
BC057617
Ensembl:
ENSMUSG00000039621
KO:
mmu:277360
|
| Nucleutide sequences |
EMBL-CDS:
BAC41161.1,
BAD32446.1,
AAH57617.1
Ensembl_TRS:
ENSMUST00000109246,
ENSMUST00000036719
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104869,
ENSMUSP00000037180
RefSeq:
NP_808450.2
|
| Others |
UniRef100:
UniRef100_Q69ZK0
UniRef90:
UniRef90_Q69ZK0
UniRef50:
UniRef50_Q8TCU6
UniGene:
Mm.34420,
Mm.491336
CCDS:
CCDS38334.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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