| Type | Description |
|---|---|
| Definition | G protein subunit alpha i1 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-27 14:39:00 | Structures of Galpha Proteins in Complex with Their Chaperone Reveal Quality Control Mechanisms. | 32126208 |
| 2020-10-03 12:56:00 | Preferential Coupling of Dopamine D2S and D2L Receptor Isoforms with Gi1 and Gi2 Proteins-In Silico Study. | 31936673 |
| 2020-08-22 15:25:00 | Orexin-A protects against oxygen-glucose deprivation/reoxygenation-induced cell damage by inhibiting endoplasmic reticulum stress-mediated apoptosis via the Gi and PI3K signaling pathways. | 31233841 |
| 2020-03-28 11:16:00 | Here, we present a 2.0-A crystal structure of Galpha i in complex with the GEM motif of GIV/Girdin. Nucleotide exchange assays, molecular dynamics simulations, and hydrogen-deuterium exchange experiments demonstrate that GEM binding to the conformational switch II causes structural changes that allosterically propagate to the hydrophobic core of the Galpha i GTPase domain | 31363053 |
| 2020-03-28 10:39:00 | the structures of the glucagon receptor (GCGR) bound to glucagon and distinct classes of heterotrimeric G proteins, Gs or Gi1 was determined using cryo-electron microscopy | 32193322 |
| Type | IDs |
|---|---|
| Synonymous | Gi |
| Gene |
UniProtKB-ID:
GNAI1_HUMAN
UniprotKB:
P63096
UniParc:
UPI0000D4CA6B,
UPI000000124A
EMBL:
AC080066,
AK304442,
M20594,
BC026326,
M17219,
M20595,
AC004159,
BT019775,
AK292953,
AF493905,
AL049933,
AF055013,
CH471091,
M20596
Ensembl:
ENSG00000127955
KO:
hsa:2770
|
| Nucleutide sequences |
EMBL-CDS:
AAV38580.1,
AAH26326.1,
CAB43212.2,
AAA35893.1,
BAG65263.1,
EAW77011.1,
AAM12619.1,
BAF85642.1,
AAA52581.1,
AAC09361.1
Ensembl_TRS:
ENST00000648832,
ENST00000649796,
ENST00000648306,
ENST00000648663,
ENST00000351004,
ENST00000457358,
ENST00000649267,
ENST00000442586,
ENST00000648877,
ENST00000649487,
ENST00000649225,
ENST00000648953,
ENST00000649855,
ENST00000648476,
ENST00000648412,
ENST00000648098
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000497260,
ENSP00000343027,
ENSP00000497051,
ENSP00000497717,
ENSP00000410572,
ENSP00000497773,
ENSP00000497315,
ENSP00000496800,
ENSP00000496829,
ENSP00000498091,
ENSP00000391439,
ENSP00000497760,
ENSP00000497379,
ENSP00000497179,
ENSP00000497754,
ENSP00000497765
RefSeq:
NP_001243343.1,
NP_002060.4
|
| Others |
UniRef100:
UniRef100_P63096
UniRef90:
UniRef90_P63096
UniRef50:
UniRef50_P63096
UniGene:
Hs.134587
CCDS:
CCDS5595.1,
CCDS59061.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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Ensembl: {{protein.nucleotideEnsembl}} |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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