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2769 GNA15

2769

GNA15

G protein subunit alpha 15

protein-coding

Homo sapiens

基因描述

Type Description
Definition G protein subunit alpha 15

研究结论

Date Results Publications
2015-12-19 11:40:00 GNA15 was not expressed in normal neuroendocrine cells but was overexpressed in gastroenteropancreatic neuroendocrine neoplasia cell lines. 25701539
2014-08-30 10:41:00 Data indicate the importance of Galpha16 as a downstream effector of the non-canonical Wnt signaling pathway and as a potential therapeutic target for the treatment of non small cell lung cancer. 24204697
2013-08-31 10:42:00 G15 ectopic presence could functionally contribute to the transformation process since siRNA-induced depletion of Galpha15 in pancreatic carcinoma cell lines dramatically inhibited anchorage-independent growth and resistance to the lack of nutrients. 23200847
2012-07-02 11:24:00 This paper shows how G alpha 15 and other Gq class members phosphorylate PKD in differing patterns 22227248
2012-07-02 11:24:00 The paper describes G alpha 15 resistance to arrestin-desensitization making it differ from other heterotrimeric G proteins (Gq, Gs, Gi, G12/13 class) 19275934

名称对应

Type IDs
Synonymous GNA16
Gene
UniProtKB-ID: GNA15_HUMAN
UniprotKB: P30679
UniParc: UPI000013D36D
EMBL: AF493904, GU727637, AC005264, AC005262, GU727645, CH471139, M63904, BC013585, BT009850
Ensembl: ENSG00000060558
KO: hsa:2769
Nucleutide sequences
EMBL-CDS: AAH13585.1, ADU87646.1, AAC25612.1, AAP88852.1, ADU87639.1, AAC25616.1, AAM12618.1, EAW69338.1, AAA35860.1
Ensembl_TRS: ENST00000262958
Protein sequencees
Ensembl_PRO: ENSP00000262958
RefSeq: NP_002059.3
Others
UniRef100: UniRef100_P30679
UniRef90: UniRef90_P30679
UniRef50: UniRef50_P30679
UniGene: Hs.73797
CCDS: CCDS12104.1

全选

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研究热度

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