| Type | Description |
|---|---|
| Definition | G protein subunit alpha 12 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 13:02:00 | G12/13 is activated by acute tethered agonist exposure in the adhesion GPCR ADGRL3. | 32778842 |
| 2018-08-04 11:13:00 | Galpha12 plays a crucial role in human airway smooth muscle contraction via RhoA-dependent activation of the PI3K/ROCK axis; targeting Galpha12 signaling may elucidate novel therapeutic targets in asthma | 28921504 |
| 2017-06-03 10:48:00 | the current studies provide evidence showing that c-Jun directly binds to a consensus binding sequence within the GNA12-5' regulatory region, thereby regulating GNA12 transcription. | 28394299 |
| 2016-08-20 10:18:00 | we conclude that Galpha12 protects HUVECs[ human umbilical vein endothelial cells ] from serum withdrawal-induced apoptosis by retaining miR-155 expression. | 26632408 |
| 2016-07-30 11:48:00 | RGS22 acts as a tumor suppressor, repressing human pancreatic adenocarcinoma cell migration by coupling to GNA12/13. | 26323264 |
| Type | IDs |
|---|---|
| Synonymous | NNX3, RMP, gep |
| Gene |
UniProtKB-ID:
GNA12_HUMAN,
Q6ZQV4_HUMAN,
E9PC54_HUMAN
UniprotKB:
Q03113,
Q6ZQV4,
E9PC54
UniParc:
UPI0000E5AD8D,
UPI00004A28C7,
UPI00001C1074,
UPI0001914C0F,
UPI000013DA5B
EMBL:
AK128701,
CH236953,
L01694,
BC087537,
BC111464,
AC004933,
AK295830,
AF493901,
AC006028,
AK127842
Ensembl:
ENSG00000146535
KO:
hsa:2768
|
| Nucleutide sequences |
EMBL-CDS:
EAL23961.1,
BAH12193.1,
AAH87537.1,
AAA35867.1,
AAM12615.1,
AAD05026.1,
AAP21870.1,
BAG54584.1,
AAI11465.1,
BAC87579.1
Ensembl_TRS:
ENST00000407904,
ENST00000275364,
ENST00000407653
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000275364,
ENSP00000385935,
ENSP00000386054
RefSeq:
NP_001269370.1,
NP_001280021.1,
NP_001269369.1,
NP_031379.2
|
| Others |
UniRef100:
UniRef100_E9PC54,
UniRef100_Q6ZQV4,
UniRef100_Q03113
UniRef90:
UniRef90_A0A2I3MSV6,
UniRef90_Q03113,
UniRef90_G3WI14
UniRef50:
UniRef50_C3Z6Y6,
UniRef50_G3WI14,
UniRef50_Q03113
UniGene:
Hs.487341
CCDS:
CCDS5335.1,
CCDS64584.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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