| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 5A |
| Date | Results | Publications |
|---|---|---|
| 2020-10-03 12:35:00 | The eIF5A (eIF5A(H)) promotes the efficient expression of a subset of mitochondrial proteins involved in the TCA cycle and oxidative phosphorylation (OXPHOS). | 31130465 |
| 2020-09-19 16:28:00 | Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission. | 32817651 |
| 2015-10-24 11:30:00 | our results provide the first genetic evidence that the hypusine modification in eIF-5A is crucial for homeostasis in mammals | 26037925 |
| 2012-06-02 10:21:00 | knockout of either the eIF5A-1 gene (Eif5a) or of the deoxyhypusine synthase gene (Dhps) caused early embryonic lethality in mice, indicating the essential nature of both eIF5A-1 and deoxyhypusine synthase in mammalian development | 21850436 |
| 2010-10-23 10:53:00 | These results point to a new functional role for eIF5A, relating it to embryogenesis, development, and cell differentiation. | 20458750 |
| Type | IDs |
|---|---|
| Synonymous | AA410058, D19Wsu54e, Eif4d, Eif5a1, eIF-4D, eIF-5A, eIF-5A-1, eIF-5A1 |
| Gene |
UniProtKB-ID:
IF5A1_MOUSE
UniprotKB:
P63242
UniParc:
UPI0000006BEE
EMBL:
AK011470,
AY129324,
AY129323,
AK011306,
BC008093,
AY129329,
BC003889,
AY129328,
AY129327,
AL596185,
BC024899,
AY129325,
AY129326,
AK149705
Ensembl:
ENSMUSG00000078812
KO:
mmu:276770
|
| Nucleutide sequences |
EMBL-CDS:
AAN17528.1,
AAN17527.1,
CAI35153.1,
BAB27641.1,
BAE29039.1,
AAN17534.1,
AAN17532.1,
AAH08093.1,
CAI35154.1,
AAN17539.1,
AAN17535.1,
AAN17521.1,
BAB27532.1,
AAH24899.1,
AAH03889.1
Ensembl_TRS:
ENSMUST00000108608,
ENSMUST00000108611,
ENSMUST00000108612,
ENSMUST00000108613,
ENSMUST00000164359,
ENSMUST00000043419,
ENSMUST00000070996,
ENSMUST00000108610,
ENSMUST00000108607,
ENSMUST00000108609,
ENSMUST00000071026
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000104247,
ENSMUSP00000104253,
ENSMUSP00000047008,
ENSMUSP00000104251,
ENSMUSP00000067077,
ENSMUSP00000104252,
ENSMUSP00000104249,
ENSMUSP00000104250,
ENSMUSP00000132717,
ENSMUSP00000104248,
ENSMUSP00000068651
RefSeq:
NP_001160068.1,
NP_001160063.1,
XP_030101911.1,
NP_001160067.1,
XP_036012632.1,
NP_001160065.1,
XP_011247360.1,
NP_001160062.1,
NP_853613.1,
NP_001160066.1,
NP_001160064.1,
NP_001160061.1,
XP_030101910.1
|
| Others |
UniRef100:
UniRef100_P63241
UniRef90:
UniRef90_P63241
UniRef50:
UniRef50_P63241
UniGene:
Mm.18026,
Mm.486207
CCDS:
CCDS24923.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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