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2764 GMFB

2764

GMFB

glia maturation factor beta

protein-coding

Homo sapiens

基因描述

Type Description
Definition glia maturation factor beta

研究结论

Date Results Publications
2019-02-09 10:49:00 GMF acts as an important upstream regulator of PGC-1alpha in promoting dopaminergic neuronal death through its effect on oxidative stress-mediated apoptosis. 29383690
2019-01-19 12:28:00 GMF and ApoE4 were strongly expressed and co-associated in amyloid plaques (APs) and in the reactive astrocytes surrounding APs in Alzheimer's disease. 29172001
2018-02-24 11:19:00 GMF-beta is an important player in glioma progression via promoting neovascularization. 26515590
2013-02-23 10:59:00 The distribution of GMF-immunoreactive cells in and around amyloid plaques and neurofibrillary tangles suggests involvement of GMF in inflammatory responses through reactive glia and a role of GMF in Alzheimer disease pathology. 22035352
2012-06-30 11:19:00 GMF co-localizes with amyloid plaques and neurofibrillary tangles in Alzheimer brains, implicating significant upregulation of GMF expression under conditions of neurodegeneration. 21835226

名称对应

Type IDs
Synonymous GMF
Gene
UniProtKB-ID: GMFB_HUMAN
UniprotKB: P60983
UniParc: UPI0000161C06
EMBL: AK311753, BT006784, CR542113, AB001106, BC005359, CH471061, M86492
Ensembl: ENSG00000197045
KO: hsa:2764
Nucleutide sequences
EMBL-CDS: BAA19232.1, CAG46910.1, BAG34696.1, AAH05359.1, AAP35430.1, AAA58614.1, EAW80638.1
Ensembl_TRS: ENST00000358056, ENST00000616146
Protein sequencees
Ensembl_PRO: ENSP00000479543, ENSP00000350757
RefSeq: NP_004115.1
Others
UniRef100: UniRef100_P60983
UniRef90: UniRef90_P60983
UniRef50: UniRef50_P60983
UniGene: Hs.151413
CCDS: CCDS9718.1

全选

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研究热度

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