| Type | Description |
|---|---|
| Definition | GM2 ganglioside activator |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:30:00 | GM2-GM3 gangliosides ratio is dependent on GRP94 through down-regulation of GM2-AP cofactor in brain metastasis cells. | 31578452 |
| 2017-11-26 01:38:00 | Review of GM2A mutations causing GM2 activator protein deficiency and GM2 gangliosidosis-AB variant. | 27402091 |
| 2017-02-04 12:38:00 | Studies indicate that sphingolipid activator proteins (SAPs) and anionic lipids are essential stimulators to reach physiological rates of lysosomal sphingolipid degradation. | 27157270 |
| 2017-02-04 11:54:00 | this study has established the potential role of GM2A in breast cancer progression | 27002480 |
| 2016-05-28 10:27:00 | Mobilization of membrane lipids by GM2AP was also inhibited in the presence of cholesterol or SM, as revealed by surface plasmon resonance studies | 26175473 |
| Type | IDs |
|---|---|
| Synonymous | GM2-AP, SAP-3 |
| Gene |
UniProtKB-ID:
SAP3_HUMAN
UniprotKB:
P17900
UniParc:
UPI00001AEC37
EMBL:
M76477,
AF124717,
AF124719,
AK312494,
AC008385,
X62078,
CH471062,
AF124718,
X16087,
BC009273,
L01439,
X61095
Ensembl:
ENSG00000196743
KO:
hsa:2760
|
| Nucleutide sequences |
EMBL-CDS:
AAA35907.1,
AAA52767.1,
CAA43993.1,
AAH09273.1,
EAW61680.1,
AAD25741.1,
CAA34215.1,
CAA43994.1,
EAW61681.1,
CAA43408.1,
BAG35396.1
Ensembl_TRS:
ENST00000357164
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000349687
RefSeq:
NP_001161079.1,
NP_000396.2
|
| Others |
UniRef100:
UniRef100_P17900
UniRef90:
UniRef90_P17900
UniRef50:
UniRef50_P17900
UniGene:
Hs.483873
CCDS:
CCDS4313.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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