| Type | Description |
|---|---|
| Definition | glutamate dehydrogenase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-13 10:09:00 | Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease. | 33093440 |
| 2020-02-29 11:04:00 | present data, showing that GLUD2 expression in Tg mice improves in vivo glucose homeostasis by boosting fasting serum insulin levels, suggest that evolutionary adaptation of hGDH2 has enabled humans to achieve narrow-range euglycemia by regulating glutamate-mediated basal insulin secretion | 31400387 |
| 2019-08-31 12:19:00 | The autoantibodies to GluD2 are common in patients with OMAS, bind to surface determinants, and are potentially pathogenic. | 30045961 |
| 2019-03-16 12:15:00 | In HEK293 cell lines GDH2 and GDH1 were over-expressed and found to be co-localized in subcellular fractions. | 29943084 |
| 2019-03-16 10:59:00 | GLUD2 overexpression inhibited Glioblastoma (GBM) cell growth suggesting a novel potential drug target for control of GBM progression. The possibility to enhance GLUD2 activity in GBM could result in a blocked/reduced proliferation of GBM cells without affecting the survival of the surrounding neurons. | 30314897 |
| Type | IDs |
|---|---|
| Synonymous | GDH2, GLUDP1 |
| Gene |
UniProtKB-ID:
DHE4_HUMAN,
A0A140VK14_HUMAN
UniprotKB:
P49448,
A0A140VK14
UniParc:
UPI0000129301
EMBL:
AC006144,
BC050732,
U08997,
HM005554,
X66310,
AK313356
Ensembl:
ENSG00000182890,
ENSG00000288118
KO:
hsa:2747
|
| Nucleutide sequences |
EMBL-CDS:
AAD05030.1,
CAA46995.1,
AAH50732.1,
BAG36157.1,
AAA20969.1,
AEE61151.1
Ensembl_TRS:
ENST00000673493,
ENST00000328078
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000500546,
ENSP00000327589
RefSeq:
NP_036216.2
|
| Others |
UniRef100:
UniRef100_P49448
UniRef90:
UniRef90_P49448
UniRef50:
UniRef50_P00367
UniGene:
Hs.368538
CCDS:
CCDS14603.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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