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2745 GLRX

2745

GLRX

glutaredoxin

protein-coding

Homo sapiens

基因描述

Type Description
Definition glutaredoxin

研究结论

Date Results Publications
2021-04-13 10:12:00 Activation of 3-Mercaptopyruvate Sulfurtransferase by Glutaredoxin Reducing System. 32481517
2021-02-27 13:47:00 Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases. 32948023
2020-06-27 10:20:00 Research on Grx and its potential roles in Parkinson's disease (PD) presents a complex situation where Grx1 likely plays a primary neuroprotective role in dopaminergic neurons but a proinflammatory role in microglia. Midbrain PD samples showed decreased Grx1 specifically within dopaminergic neurons. Increased GLRX copy number in PD patients was associated with earlier onset.[review] 29183158
2019-12-07 11:02:00 The glutaredoxin (Grx) is involved in the formation, transfer or isomerization of disulfide bonds through a characteristic thiol-disulfide exchange reaction. 30367780
2019-10-05 11:10:00 Patients who experienced a stroke or myocardial infarction at any time had a significantly higher increase in Grx during the 2 years of dialysis 30253414

名称对应

Type IDs
Synonymous GRX, GRX1
Gene
UniProtKB-ID: GLRX1_HUMAN, A0A024RAM2_HUMAN
UniprotKB: P35754, A0A024RAM2
UniParc: UPI0000111F53
EMBL: BC005304, CR542165, AK311868, AF162769, BC106075, CR450312, X76648, CH471084, AF115104, DQ026062, D21238, BT006689, AF069668, BC010965, AF115105
Ensembl: ENSG00000173221
KO: hsa:2745
Nucleutide sequences
EMBL-CDS: AAP35335.1, AAH05304.1, AAD43353.1, CAA54094.1, AAY29058.1, AAI06076.1, EAW96056.1, CAG46962.1, CAG29308.1, AAC35798.1, BAG34809.1, BAA04769.1, AAC98318.1, AAH10965.1, EAW96057.1
Gene_ORFName: hCG_36838
Ensembl_TRS: ENST00000379979, ENST00000237858, ENST00000505427, ENST00000508780, ENST00000512469
Protein sequencees
Ensembl_PRO: ENSP00000427353, ENSP00000422708, ENSP00000424636, ENSP00000369314, ENSP00000237858
RefSeq: NP_001230588.1, NP_002055.1, NP_001230587.1, NP_001112362.1
Others
UniRef100: UniRef100_P35754
UniRef90: UniRef90_P35754
UniRef50: UniRef50_P35754
UniGene: Hs.28988
CCDS: CCDS4078.1

全选

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