| Type | Description |
|---|---|
| Definition | DNA polymerase mu |
| Date | Results | Publications |
|---|---|---|
| 2021-03-28 19:07:00 | DNA polymerase mu: An inflexible scaffold for substrate flexibility. | 33087269 |
| 2019-01-12 10:36:00 | pol mu-mediated deoxyguanosine triphosphate mismatch insertion opposite template base T coupled with ligation could be a feature of mutation prone nonhomologous end joining during double-strand break repair. | 30310068 |
| 2017-12-02 10:54:00 | Polmu point mutations affecting 2 conserved adjacent residues located in the 8 kDa domain, G174S and R175H, limit the efficiency of accurate NHEJ by Polmu in vitro and in vivo due to decreased template dependency during NHEJ, which renders the error-rate of the mutants higher due to the ability of Polmu to randomly incorporate nucleotides at DSBs. | 28973441 |
| 2017-10-14 13:10:00 | Structural accommodation of ribonucleotide incorporation by the DNA repair enzyme polymerase Mu has been described. | 28911097 |
| 2016-04-30 10:25:00 | analysis of template-dependent synthesis by human polymerase mu | 26240373 |
| Type | IDs |
|---|---|
| Synonymous | Pol Mu, Tdt-N |
| Gene |
UniProtKB-ID:
DPOLM_HUMAN
UniprotKB:
Q9NP87
UniParc:
UPI000004129C,
UPI0000DDA01D,
UPI0000225638
EMBL:
CH471128,
AY899911,
AF176097,
BC049202,
AJ131891,
AC017116,
BC062590
Ensembl:
ENSG00000122678
KO:
hsa:27434
|
| Nucleutide sequences |
EMBL-CDS:
EAW61122.1,
CAB65075.2,
EAW61124.1,
AAW65376.1,
EAW61123.1,
EAW61126.1,
AAF26284.1,
AAH49202.2,
AAH62590.1
Ensembl_TRS:
ENST00000335195,
ENST00000395831,
ENST00000242248
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000242248,
ENSP00000335141,
ENSP00000379174
RefSeq:
NP_001271259.1,
NP_037416.1,
NP_001349612.1,
NP_001271260.1
|
| Others |
UniRef100:
UniRef100_Q9NP87
UniRef90:
UniRef90_Q9NP87
UniRef50:
UniRef50_Q9NP87
UniGene:
Hs.596982
CCDS:
CCDS64635.1,
CCDS34625.1,
CCDS64636.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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