| Type | Description |
|---|---|
| Definition | HtrA serine peptidase 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:35:00 | Expression of HTRA Genes and Its Association with Microsatellite Instability and Survival of Patients with Colorectal Cancer. | 32486357 |
| 2021-01-02 12:48:00 | Intrafamilial ""DOA-plus"" phenotype variability related to different OMI/HTRA2 expression. | 31609081 |
| 2020-06-20 11:20:00 | Suppressing HtrA2/Omi expression promotes hepatic fibrogenesis via modulating mitochondrial reactive oxygen species generation; these novel mechanistic insights involving the regulation of mitochondrial homeostasis by HtrA2/Omi may be of importance for developing new therapeutic strategies for hepatic fibrosis. | 31547195 |
| 2020-04-04 12:22:00 | Data show that extracellular serine protease high-temperature-required protein A2 (HtrA2) induces apoptosis in endothelial cells, but the exact molecular mechanisms have to be investigated in future. | 31683713 |
| 2019-12-21 10:57:00 | the results demonstrate increased levels of the mitochondrial serine protease OMI/HTRA2, and a coherent pattern of association between the activated form of OMI/HTRA2 and several key proteins involved in Alzheimer's disease pathology. | 30361890 |
| Type | IDs |
|---|---|
| Synonymous | MGCA8, OMI, PARK13, PRSS25 |
| Gene |
UniProtKB-ID:
HTRA2_HUMAN,
A0A384MDW9_HUMAN
UniprotKB:
O43464,
A0A384MDW9
UniParc:
UPI000002AB57,
UPI000012CB84,
UPI000002AB59,
UPI000002AB58
EMBL:
AF141305,
AF020760,
AF184911,
AF141307,
BC000096,
GQ900899,
AC006544,
CH471053,
AF141306
Ensembl:
ENSG00000115317
KO:
hsa:27429
|
| Nucleutide sequences |
EMBL-CDS:
AAF66598.1,
AAF66596.1,
AAG13126.1,
AAF66597.1,
AAH00096.1,
AAB94569.2,
EAW99621.1,
ADO22416.1
Gene_ORFName:
hCG_41061
Ensembl_TRS:
ENST00000352222,
ENST00000258080
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258080,
ENSP00000312893
RefSeq:
NP_659540.1,
NP_001308657.1,
NP_037379.1,
NP_001308656.1
|
| Others |
UniRef100:
UniRef100_O43464
UniRef90:
UniRef90_O43464
UniRef50:
UniRef50_O43464
UniGene:
Hs.469045,
Hs.744841
CCDS:
CCDS1952.1,
CCDS1951.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员