| Type | Description |
|---|---|
| Definition | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 10:24:00 | Abcc6 was confirmed as a major determinant for ectopic mineralization in multiple tissues. Integrative analysis using functional genomics tools that included GeneWeaver, String, and Mouse Genome Informatics identified a total of nine additional candidate modifier genes that could influence the organ-specific ectopic mineralization phenotypes | 31207231 |
| 2019-03-23 10:23:00 | Abcc6 deficiency in mice leads to altered ABC transporter gene expression in metabolically active tissues. | 30611276 |
| 2017-11-04 12:40:00 | abrogated ABCC6 function does cause alterations in the metabolic profile of the liver in accordance with PXE being a metabolic disease originating from liver disturbance | 27758107 |
| 2016-01-02 11:26:00 | bisphosphonates may be helpful for prevention of mineral deposits in Pseudoxanthoma elasticum and generalized arterial calcification of infancy caused by mutations in the ABCC6 gene. | 25607347 |
| 2015-09-05 11:54:00 | In a mouse model of CKD, ABCC6 protein expression was decreased in liver and kidney, however mRNA levels were unchanged. | 24994603 |
| Type | IDs |
|---|---|
| Synonymous | Abcc1b, DCC, Dyscalc1, Mrp6, dyscalc |
| Gene |
UniProtKB-ID:
MRP6_MOUSE
UniprotKB:
Q9R1S7
UniParc:
UPI0000020C9F
EMBL:
AC115036,
BC049980,
EF109741,
EF109740,
AB028737
Ensembl:
ENSMUSG00000030834
KO:
mmu:27421
|
| Nucleutide sequences |
EMBL-CDS:
BAA83820.1,
ABM89088.1,
AAH49980.1,
ABM89087.1
Ensembl_TRS:
ENSMUST00000002850
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000002850
RefSeq:
NP_061265.2,
XP_006541009.1,
XP_006541011.1,
XP_006541012.1,
XP_006541010.1
|
| Others |
UniRef100:
UniRef100_Q9R1S7
UniRef90:
UniRef90_O88269
UniRef50:
UniRef50_O95255
UniGene:
Mm.63514
CCDS:
CCDS21272.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员