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27413 Abcb11

27413

Abcb11

ATP-binding cassette, sub-family B (MDR/TAP), member 11

protein-coding

Mus musculus

基因描述

Type Description
Definition ATP-binding cassette, sub-family B (MDR/TAP), member 11

研究结论

Date Results Publications
2021-03-27 14:41:00 Tanshinone IIA prevents rifampicin-induced liver injury by regulating BSEP/NTCP expression via epigenetic activation of NRF2. 31571363
2020-10-03 12:59:00 Heterozygous knockout of Bile salt export pump ameliorates liver steatosis in mice fed a high-fat diet. 32785220
2018-10-06 12:10:00 Studied effect of endotoxin exposure on liver following partial hepatectomy; found endotoxin exposure induced autoantibody production against Bsep (bile salt export pump) leading to dysfunction of hepatobiliary transporter systems. 29850541
2016-07-16 11:05:00 Isoniazid/rifampicin administration significantly down-regulated the expression of hepatic bile acids transporters Ntcp and Bsep in liver. 25886055
2015-05-02 12:56:00 mechanism of increased biliary lipid secretion in Bsep-/- mice is based on increased expression of the responsible canalicular transporter proteins. 25552583

名称对应

Type IDs
Synonymous ABC16, Bsep, Lith1, PFIC2, PGY4, SPGP
Gene
UniProtKB-ID: ABCBB_MOUSE
UniprotKB: Q9QY30
UniParc: UPI00001EF1CB
EMBL: AF133903, AF186585, CH466519, AL929170
Ensembl: ENSMUSG00000027048
KO: mmu:27413
Nucleutide sequences
EMBL-CDS: EDL27032.1, AAD56419.1, AAF14372.1
Ensembl_TRS: ENSMUST00000102710, ENSMUST00000102709
Protein sequencees
Ensembl_PRO: ENSMUSP00000099770, ENSMUSP00000099771
RefSeq: NP_001350421.1, XP_006499733.1, NP_066302.2
Others
UniRef100: UniRef100_Q9QY30
UniRef90: UniRef90_Q9QY30
UniRef50: UniRef50_O95342
UniGene: Mm.439855
CCDS: CCDS16090.1

全选

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研究热度

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