| Type | Description |
|---|---|
| Definition | solute carrier family 14 (urea transporter), member 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-16 15:54:00 | The urea transporter UT-A1 plays a predominant role in a urea-dependent urine-concentrating mechanism. | 32461256 |
| 2020-07-18 12:20:00 | Reduced UT-A1/A3 activity reduces the severity of renal fibrosis following unilateral ureteral obstruction. | 32174141 |
| 2020-01-11 10:52:00 | In summary, loss of both UT-A1 and UT-A3 (but not UT-A3 alone) causes elevated medullary NO production and salt wasting | 30539654 |
| 2017-11-04 11:37:00 | Functional deficiency of all UTs caused a urea-selective urine-concentrating defect with little physiological abnormality in extrarenal organs. | 27914708 |
| 2017-03-04 10:07:00 | results suggest that GSK3 may in part modulate the hypertonic-induced intracellular UT-A1 redistribution and its accumulation on the plasma membrane, which may constitute another mechanism by which GSK3 modulates urine concentration | 27161213 |
| Type | IDs |
|---|---|
| Synonymous | UT-A1, UT-A3 |
| Gene |
UniProtKB-ID:
UT2_MOUSE,
G5E849_MOUSE,
A0A0R4J213_MOUSE,
A0A494BAL3_MOUSE,
Q8BMD1_MOUSE
UniprotKB:
Q8R4T9,
G5E849,
A0A0R4J213,
A0A494BAL3,
Q8BMD1
UniParc:
UPI00000223A3,
UPI0001C67AAB,
UPI00000EB34B,
UPI0000192DBF,
UPI0001C67AA9,
UPI00000E6D82,
UPI0001C67AAC,
UPI0001C67AAA
EMBL:
AK032837,
AF258601,
BC150680,
CH466528,
AC151578,
AF366052,
AF367359,
AC112792,
AF258602,
AC145554,
AC140455
Ensembl:
ENSMUSG00000024552
KO:
mmu:27411
|
| Nucleutide sequences |
EMBL-CDS:
AAM00357.1,
AAG32168.1,
AAM21206.1,
EDL09434.1,
AAG32167.1,
AAI50681.1,
BAC28051.1
Ensembl_TRS:
ENSMUST00000237674,
ENSMUST00000025434,
ENSMUST00000163367,
ENSMUST00000235389,
ENSMUST00000237290
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025434,
ENSMUSP00000157851,
ENSMUSP00000126416,
ENSMUSP00000158141,
ENSMUSP00000157855
RefSeq:
NP_109608.1,
NP_997534.2,
NP_001103744.1,
NP_001103743.1,
XP_017173404.1,
XP_006526551.1
|
| Others |
UniRef100:
UniRef100_Q8R4T9,
UniRef100_G5E849,
UniRef100_A0A494BAL3
UniRef90:
UniRef90_Q8R4T9-3,
UniRef90_Q62668
UniRef50:
UniRef50_Q8R4T9-3,
UniRef50_Q15849
UniGene:
Mm.44158
CCDS:
CCDS89284.1,
CCDS89283.1,
CCDS50331.1,
CCDS29361.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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