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274 BIN1

274

BIN1

bridging integrator 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition bridging integrator 1

研究结论

Date Results Publications
2021-04-13 10:07:00 Microglia Implicated in Tauopathy in the Striatum of Neurodegenerative Disease Patients from Genotype to Phenotype. 32842621
2021-01-09 13:30:00 Alzheimer Gene BIN1 may Simultaneously Influence Dementia Risk and Androgen Deprivation Therapy Dosage in Prostate Cancer. 32568785
2020-10-24 14:02:00 BIN1 favors the spreading of Tau via extracellular vesicles. 31263146
2020-08-22 15:30:00 MiR-744 mediates the Oxaliplatin chemoresistance in colorectal cancer through inhibiting BIN1. 31884801
2020-08-01 12:50:00 we found that hypomethylation levels at specific CpGs in BIN1, rather than in the whole open sea region, elevated the risk for late onset Alzheimer's Disease (LOAD). We also found that hypomethylation at specific CpGs (26, 44, and 87) increased the risks for LOAD. 31335457

名称对应

Type IDs
Synonymous AMPH2, AMPHL, CNM2, SH3P9
Gene
UniProtKB-ID: BIN1_HUMAN, A0A024RAE9_HUMAN, A0A024RAI5_HUMAN, A0A024RAJ2_HUMAN, A0A024RAG8_HUMAN, A0A024RAF6_HUMAN, A0A024RAG9_HUMAN, A0A024RAF0_HUMAN, A0A024RAI4_HUMAN, Q9BTH3_HUMAN, B7Z2Z2_HUMAN, A0A024RAF1_HUMAN, B7Z6Y2_HUMAN, A0A024RAJ3_HUMAN, A0A024RAI6_HUMAN
UniprotKB: O00499, A0A024RAE9, A0A024RAI5, A0A024RAJ2, A0A024RAG8, A0A024RAF6, A0A024RAG9, A0A024RAF0, A0A024RAI4, Q9BTH3, B7Z2Z2, A0A024RAF1, B7Z6Y2, A0A024RAJ3, A0A024RAI6
UniParc: UPI000002A4D6, UPI000002A4D1, UPI0001915112, UPI000002A4D3, UPI000002A4CF, UPI000002A4D7, UPI0001914CAE, UPI000002A4D5, UPI0000070435, UPI000002A4D4, UPI000002A4D2, UPI000002A4D8, UPI0000001303, UPI000002A4D0
EMBL: AK301153, AL713697, U84002, U87558, AK295300, AF068917, BT006865, U68485, CH471103, AC012508, AF068914, AF043900, BC004101, U83999, AF043901, AF043899, U84004, AF043898, AF001383, U84003, AF068918, AF068915, AF004015, AF070576, AF068916, U84001
Ensembl: ENSG00000136717
KO: hsa:274
Nucleutide sequences
EMBL-CDS: EAW95302.1, AAC51345.1, AAC39713.1, AAC23440.1, AAC24127.1, AAB63263.1, AAC39711.1, AAB61363.1, AAC23751.1, AAC24128.1, AAC24126.1, AAC23441.1, AAC28646.1, AAC23750.1, AAC39712.1, AAC39710.1, AAY24328.1, AAC17461.1, CAD28496.1, EAW95293.1, EAW95290.1, EAW95286.1, EAW95294.1, EAW95300.1, EAW95296.1, EAW95292.1, EAW95301.1, EAW95307.1, EAW95291.1, EAW95299.1, EAW95306.1, EAW95288.1, EAW95298.1, EAW95289.1, EAW95287.1, AAP35511.1, AAH04101.1, BAH12028.1, EAW95303.1, BAH13418.1, EAW95297.1, EAW95305.1, EAW95295.1, EAW95304.1
Gene_ORFName: hCG_40441, hCG_40441, hCG_40441, hCG_40441, hCG_40441, hCG_40441, hCG_40441, hCG_40441, hCG_40441, hCG_40441, hCG_40441
Ensembl_TRS: ENST00000376113, ENST00000357970, ENST00000351659, ENST00000409400, ENST00000393040, ENST00000393041, ENST00000348750, ENST00000316724, ENST00000346226, ENST00000259238, ENST00000352848
Protein sequencees
Ensembl_PRO: ENSP00000376760, ENSP00000259237, ENSP00000365281, ENSP00000316779, ENSP00000376761, ENSP00000315284, ENSP00000315411, ENSP00000350654, ENSP00000259238, ENSP00000386797, ENSP00000315388
RefSeq: NP_647597.1, NP_647599.1, NP_647594.1, NP_647598.1, NP_001307561.1, NP_001307571.1, NP_647601.1, NP_004296.1, NP_001307562.1, NP_001307569.1, NP_647593.1, NP_647595.1, NP_647596.1, NP_001307570.1, NP_001307563.1, NP_647600.1
Others
UniRef100: UniRef100_A0A024RAI5, UniRef100_A0A024RAF0, UniRef100_A0A024RAI4, UniRef100_B7Z2Z2, UniRef100_A0A024RAE9, UniRef100_B7Z6Y2, UniRef100_A0A024RAG8, UniRef100_A0A024RAJ3, UniRef100_A0A024RAI6, UniRef100_Q9BTH3, UniRef100_A0A024RAF6, UniRef100_O00499, UniRef100_A0A024RAG9, UniRef100_A0A024RAJ2
UniRef90: UniRef90_A0A024RAJ3, UniRef90_O00499, UniRef90_A0A024RAI6, UniRef90_A0A024RAI4, UniRef90_A0A2K6V602, UniRef90_A0A024RAG9, UniRef90_B7Z6Y2, UniRef90_A0A024RAI5, UniRef90_A0A024RAJ2, UniRef90_A0A024RAF0, UniRef90_A0A024RAE9, UniRef90_A0A024RAF6
UniRef50: UniRef50_O08839-6, UniRef50_F1NZ04, UniRef50_O08839, UniRef50_O08839-5, UniRef50_A0A2Y9L205, UniRef50_O00499
UniGene: Hs.193163
CCDS: CCDS42744.1, CCDS2138.1, CCDS42743.1, CCDS2139.1, CCDS82508.1, CCDS2143.1, CCDS2141.1, CCDS46403.1, CCDS2140.1, CCDS2142.1, CCDS2137.1

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