| Type | Description |
|---|---|
| Definition | membrane metallo-endopeptidase-like 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-02-02 10:36:00 | Sustained Rho activation in NEP(-/-) pulmonary artery smooth muscle cells is associated with a decrease in SM-protein levels and increased migration and proliferation. | 29191928 |
| 2018-01-06 10:58:00 | These studies help to characterize our complex transgenic model of NEP overexpression and further demonstrate NEP's protective effects against plasma extravasation. | 27369050 |
| 2016-03-05 10:07:00 | This study demonstrated that Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the Neprilysin in mice. | 25510509 |
| 2015-10-17 11:47:00 | neprilysin x ABCC1 double-deficient mice present a new model for early effects of amyloid-beta-related mild cognitive impairment that allows investigations without artificial overexpression of inherited Alzheimer's disease genes | 25991605 |
| 2011-07-23 11:15:00 | Data show that intranasal delivery of drugs can be used to model Alzheimer disease and suggest that other phosphoramidon-sensitive peptidases are degrading amyloid beta in neprilysin/NEP2-deficient mice. | 20941644 |
| Type | IDs |
|---|---|
| Synonymous | Mell1, NEP2, NEPII, Nl1, SEP |
| Gene |
UniProtKB-ID:
MMEL1_MOUSE,
E9PVK7_MOUSE
UniprotKB:
Q9JLI3,
E9PVK7
UniParc:
UPI00000E72A4,
UPI0000033C44,
UPI00001F1DFC,
UPI0000027692
EMBL:
AF176569,
AF302077,
AF157106,
AL607032,
AF302075,
AF302076,
AK154366,
AF157105
Ensembl:
ENSMUSG00000058183
KO:
mmu:27390
|
| Nucleutide sequences |
EMBL-CDS:
AAG18447.1,
AAF69247.1,
AAG18448.1,
AAG18446.1,
AAF13153.1,
AAF13152.1,
BAE32538.1
Ensembl_TRS:
ENSMUST00000163732
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000131753
RefSeq:
NP_038811.2
|
| Others |
UniRef100:
UniRef100_Q9JLI3,
UniRef100_E9PVK7
UniRef90:
UniRef90_P0C1T0
UniRef50:
UniRef50_P0C1T0
UniGene:
Mm.116944
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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