| Type | Description |
|---|---|
| Definition | glyoxalase I |
| Date | Results | Publications |
|---|---|---|
| 2021-02-20 13:35:00 | Resveratrol, Curcumin and Piperine Alter Human Glyoxalase 1 in MCF-7 Breast | 32721999 |
| 2021-01-09 13:33:00 | LncRNA OIP5-AS1 Promotes Breast Cancer Progression by Regulating miR-216a-5p/GLO1. | 32916503 |
| 2020-08-22 15:29:00 | Glyoxalase 1 Prevents Chronic Hyperglycemia Induced Heart-Explant Derived Cell Dysfunction. | 31534514 |
| 2020-07-25 11:49:00 | The most active compound (ST018515) showed an IC50 of 0.34 +/- 0.03 muM, which, compared to reported GLO-I inhibitors, can be considered a potent inhibitor, making it a good candidate for further optimization towards designing more potent GLO-I inhibitors. | 31630312 |
| 2020-07-04 11:13:00 | Results indicate that the GLO1 loss of function (GLO1 (fs) mutation derived from the schizophrenia patient and the engineered GLO1 (-/-) mutation) impaired the cellular development of iPS cells because of the enhanced carbonyl stress. | 31591136 |
| Type | IDs |
|---|---|
| Synonymous | GLOD1, GLYI, HEL-S-74 |
| Gene |
UniProtKB-ID:
LGUL_HUMAN,
X5DNM4_HUMAN
UniprotKB:
Q04760,
X5DNM4
UniParc:
UPI000217CB41,
UPI0000169DF9
EMBL:
D13315,
KJ534846,
AL391415,
S83285,
BC001741,
L07837,
BT019988,
BT019987,
AK312662,
BC015934,
BC011365,
CH471081,
AF146651,
AK293345,
AB209801
Ensembl:
ENSG00000124767
KO:
hsa:2739
|
| Nucleutide sequences |
EMBL-CDS:
AAD38008.1,
AAV38790.1,
BAG56861.1,
AAH11365.1,
BAA02572.1,
BAG35544.1,
AAH01741.1,
AAA52565.1,
AAV38791.1,
AAH15934.1,
BAD93038.1,
AAB49495.1,
EAX03964.1,
AHW56486.1,
EAX03965.1
Gene_ORFName:
hCG_32350
Ensembl_TRS:
ENST00000373365
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362463
RefSeq:
NP_006699.2
|
| Others |
UniRef100:
UniRef100_Q04760
UniRef90:
UniRef90_Q04760
UniRef50:
UniRef50_Q04760
UniGene:
Hs.268849
CCDS:
CCDS4837.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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