| Type | Description |
|---|---|
| Definition | neuronal PAS domain protein 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-04-07 11:22:00 | Study provides a clear, unbiased view of the full spectrum of genes regulated by NPAS1 and NPAS3 and shows that these transcription factors are master regulators of neuropsychiatric function. These findings expose the molecular pathophysiology of NPAS1/3 mutations and provide a striking example of the shared, combinatorial nature of molecular pathways that underlie diagnostically distinct neuropsychiatric conditions. | 28499489 |
| 2012-06-30 11:19:00 | Most NPAS3 immunofluorescence originated in the subgranular zone of the dentate gyrus with immunopositive processes radiating into the granule cell layer proper. Npas3 acts during neuronal maturation/differentiation. | 21709683 |
| 2010-01-21 00:00:00 | Npas3-/- mice are deficient in expression of hippocampal FGF receptor subtype 1 mRNA. | 16172381 |
| 2010-01-21 00:00:00 | a regulatory program controlled in inhibitory interneurons by the NPAS1 and NPAS3 transcription factors may be either substantively or tangentially relevant to psychosis | 15347806 |
| 2010-01-21 00:00:00 | our observations indicate an important role for Npas3 in controlling normal brain development and neurosignaling pathways | 16190882 |
| Type | IDs |
|---|---|
| Synonymous | 4930423H22Rik, bHLHe12 |
| Gene |
UniProtKB-ID:
F8VQB2_MOUSE
UniprotKB:
F8VQB2
UniParc:
UPI0000021AB3
EMBL:
AC139934,
CT030137,
AC120181,
AC125451,
CR974571,
AC159634
Ensembl:
ENSMUSG00000021010
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000101432
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000098975
RefSeq:
XP_036013349.1,
XP_036013342.1,
XP_030102608.1,
XP_036013338.1,
XP_030102611.1,
XP_030102610.1,
XP_036013343.1,
XP_036013341.1,
XP_036013356.1,
NP_001357893.1,
XP_006516002.2,
XP_036013334.1,
XP_006516003.2,
XP_036013354.1,
XP_036013348.1,
XP_036013332.1,
XP_036013357.1,
NP_001357889.1,
NP_038808.3,
XP_036013347.1,
XP_030102604.2,
XP_030102605.2,
XP_036013355.1,
XP_036013352.1,
XP_006516005.1,
XP_030102614.1,
NP_001357892.1,
XP_036013333.1,
NP_001357891.1,
XP_036013351.1,
XP_030102606.2,
XP_006516004.1,
XP_036013353.1,
XP_036013337.1,
XP_036013345.1,
XP_036013344.1,
XP_036013339.1,
XP_030102616.1,
XP_036013346.1,
XP_030102612.1,
XP_036013330.1,
XP_036013335.1,
XP_030102609.1,
XP_036013336.1,
XP_036013331.1,
XP_036013350.1,
XP_036013340.1,
XP_006516001.2,
NP_001357890.1,
XP_030102607.2
|
| Others |
UniRef100:
UniRef100_F8VQB2
UniRef90:
UniRef90_Q9QZQ0
UniRef50:
UniRef50_Q9QZQ0
UniGene:
Mm.247044,
Mm.466545
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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