Dguok - deoxyguanosine kinase-BMKCloudï½ç¾è¿å®¢äº

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27369 Dguok

基因描述

Type	Description
Definition	deoxyguanosine kinase

研究结论

Date	Results	Publications
2020-03-14 10:20:00	We conclude that Dguok has a major role for the synthesis of deoxyribonucleotides for mtDNA replication particularly in the liver, similar to the human disorder. Our data also show a catabolic lipid metabolism in liver tissue of Dguok-/-.	31127938
2015-02-21 10:47:00	thymidine kinase 2 but not deoxyguanosine kinase is up-regulated during the stationary growth phase of cultured cells	24940680

名称对应

Type	IDs
Synonymous	dGK, dGK1, dGK2, dGK3
Gene	UniProtKB-ID: DGUOK_MOUSE, Q504N4_MOUSE UniprotKB: Q9QX60, Q504N4 UniParc: UPI000002134B, UPI00027DB797, UPI000019427C EMBL: U90524, CH466523, AJ133750, BC094920, AK035281, AJ133749, AC090648 Ensembl: ENSMUSG00000014554 KO: mmu:27369
Nucleutide sequences	EMBL-CDS: CAB43122.1, BAC29014.1, CAB43121.1, AAF14342.1, EDK99082.1, AAH94920.1 Ensembl_TRS: ENSMUST00000014698, ENSMUST00000113888
Protein sequencees	Ensembl_PRO: ENSMUSP00000014698, ENSMUSP00000109520 RefSeq: XP_036022092.1, NP_001155993.1, XP_011239672.1, NP_038792.2, XP_017177093.1
Others	UniRef100: UniRef100_Q9QX60 UniRef90: UniRef90_Q9QX60 UniRef50: UniRef50_Q9QX60 UniGene: Mm.42234 CCDS: CCDS20279.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
31127938	Severe mtDNA depletion and dependency on catabolic lipid metabolism in DGUOK knockout mice. Hum. Mol. Genet. Xiaoshan Zhou , Sophie Curbo , Qian Zhao , Shuba Krishnan , Raoul Kuiper , Anna Karlsson	2019-09-01	-
24940680	Mitochondrial thymidine kinase 2 but not deoxyguanosine kinase is up-regulated during the stationary growth phase of cultured cells. Nucleosides Nucleotides Nucleic Acids Ren Sun , Staffan Eriksson , Liya Wang	2014-01-01	Dguok, Tk2, DGUOK, TK2
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18614015	A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha	2008-07-11	Acacb, Hscb, Gadd45gip1, Lars2, Acad11, Chchd10, Nt5dc3, Slc25a41, Nt5m, Cyp27a1, Acly, Ndufb11, Gldc, Rexo2, Rars, Aldh6a1, Slc25a47, Rdh14, Ppif, Ldhal6b, Me2, Glyat, Slc25a45, Acaca, Nt5c3, Mrpl10, Mrpl41, Mrpl30, Aldh1l1, Mthfs, Shmt2, Atic, Mthfd1, Mat2b, Fam210a, Gpt2, Lyrm2, Rdh13, Mtrf1l, Atad3a, Rars2, Sccpdh, Me3, Maob, Dut, Cyp11b1, Fdps, Akr7a5, Msra, Krt5, Cox6b1, Qdpr, Acat1, Acat2, Aldh7a1, Pcca, Etfb, Etfa, Nudt19, Acadl, Acadm, Acadvl, Acaa1a, Acads, Aco1, Aco2, Prosc, Afg3l1, Adsl, Agxt, Ak2, Ak4, Akap1, Alas1, Alas2, Abcd1, Aldh2, Aldh3a2, Gfer, Acsm1, Slc25a4, Slc25a5, Prdx3, Prdx6, Mrps2, Arg2, Rhoa, Atp5a1, Atp5b, Atp5c1, Atp5f1, Atp5g1, Atp5j, Atp5k, Atpif1, Auh, Akr1b7, Bad, Bak1
17967808	EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst	2007-09-01	Gm11696, Gm10589, Apela, Gm10822, Gm2085, Gm2312, Lncenc1, Gm2381, Gm2659, Gm2679, Dynlt1c, Gm3134, Gm3143, Gm3236, Gm3574, Gm3581, Gm3718, Gm3859, Gm3905, Gm3952, Gm3957, Gm3973, Gm12057, Rex2, Gm4218, Gm4225, Gm16476, Gm4407, Gm14410, Gm4420, Gm14005, 1300002E11Rik, Gm4532, Srcap, Gm17789, Gm10751, Gm14321, 0610009E02Rik, Gm12758, Gm11532, Phactr4, Rusc2, AK010878, Gm10778, 5830417I10Rik, Mir1902, Gm15270, Gm11767, Ino80dos, Bsdc1, Gm7645, Gm20590, Slc44a1, Gm15545, Gm17292, 2900009J06Rik, Kifc1, Gm13150, Gm19426, Gm19428, Gm19474, Gm14963, Gm19565, Gm19592, Gm12588, Snhg4, Gm19702, Gm19705, Platr22, Nuggc, Zfp534, Gm19860, Gm11725, Gm19876, Gm19889, Gm16201, Gm13056, Tnfsf13os, Gm19925, Gm19976, Gm20014, Gm16740, Gm20039, Gm20045, AU020206, Ccdc170, Trp53cor1, Gm20266, Gm20324, Zfp518b, Gm14401, AI480526, Pds5b, Ube3c, Gm21297, Akap9, Gm29724, Itfg2, Parp11
16602821	BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol Susan Magdaleno , Patricia Jensen , Craig L Brumwell , Anna Seal , Karen Lehman , Andrew Asbury , Tony Cheung , Tommie Cornelius , Diana M Batten , Christopher Eden , Shannon M Norland , Dennis S Rice , Nilesh Dosooye , Sundeep Shakya , Perdeep Mehta , Tom Curran	2006-04-01	-
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735
15782199	Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Nat. Methods Akira Watahiki , Kazunori Waki , Norihito Hayatsu , Toshiyuki Shiraki , Shinji Kondo , Mari Nakamura , Daisuke Sasaki , Takahiro Arakawa , Jun Kawai , Matthias Harbers , Yoshihide Hayashizaki , Piero Carninci	2004-12-01	Ldlrap1, Mfap1b, Dnajc3, Fam129c, Rsph3b, Rnaset2a, Fam174b, Gm9797, Gm2296, Gm15429, Atp6v0c-ps2, Kcnj13, Gm10291, Gm15264, Rpl3-ps1, Gm4482, Srcap, Tpt1-ps3, Rps2-ps6, Orai2-ps, Tdrd7, Sco2, Pafah2, Akna, H6pd, Stx12, Gm15590, Osbpl9, AU040320, Ppp1r8, Bsdc1, Gm37013, Slc44a1, Zfand2a, Rpl5, LOC100503956, Atg14, Rell1, Slc15a4, Noc4l, Psph, 9330133O14Rik, Mapre3, Usp30, Ube3c, Rita1, Tbc1d14, Gm21685, Chpf2, Tyw1, Rab28, Zfp513, LOC101055802, Zfp282, Snx21, Rpusd3, Itfg2, Pot1a, Tada3, Brk1, Eogt, Dhx32, Ric8a, Inpp5f, Plekhg2, Hsd3b7, Mob2, Prkd2, Vrk3, Grwd1, Pwwp2b, Spty2d1, Faap24, Ints4, Rrp8, Unc45a, Sf3b3, D8Ertd738e, Usb1, Smim19, Dohh, Fam192a, Enkd1, Prmt9, Zdhhc7, Snapc2, Gpat4, Ankrd10, Cog4, Clk3, Xylb, Imp3, Cmtm7, Ano10, Alg9, Plekho2, Mapkapk3, Acad11, Gm30491
14681479	GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. Axel Visel , Christina Thaller , Gregor Eichele	2004-01-01	Rnaset2a, Mthfsl, Tgtp2, Gm11273, Gm3063, Gm9833, Zkscan16, Amd2, Gm3776, Gm3934, Gm10681, Gm4450, Cyp2j11, Camta1, Zbtb48, Sco2, Pafah2, Akna, H6pd, Smpdl3b, Lao1, Kifc1, Gm20186, Ugt2b38, Slc15a4, Psph, Acacb, Pds5b, Ugt2b34, Ube3c, Hsd3b7, Ano1, Gpat4, Lars2, Xylb, Slc22a13, Rpp25, Acad11, Slc6a8, Slc6a15, Upb1, Mgat4b, Xpo1, Slc35e4, Pnpo, Slc25a41, Nt5m, Rpn1, Gck, Synj1, Cyp27a1, Adcy4, Adcy3, Acly, Ces1d, Gldc, Sbk1, Barhl2, E2f4, Dgkz, Rars, Cnot6, Slc16a6, Aldh6a1, Adi1, Rdh14, Iars, Akr1c18, Dusp22, Gmpr2, Thtpa, Espl1, Slc45a4, Stk38, Tecr, Ldhal6b, Ppcs, Cyp4f15, Slc39a3, Slc39a6, Me2, Lars, Cyp2c50, Carns1, Yars, Psat1, Slc25a45, Acaca, Atf5, Eprs, Nt5c3, Dio3, Ovol2, Pi4kb, Uap1, Slc12a6, Aldh1l1, Haao, Scml2

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