| Type | Description |
|---|---|
| Definition | serine racemase |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:28:00 | Postsynaptic Serine Racemase Regulates NMDA Receptor Function. | 33158959 |
| 2020-06-27 10:08:00 | Serine racemase knockout mice demonstrate abnormalities in socio-communicative behaviors consistent with an impairment in sociality, a negative symptom of schizophrenia. | 31515952 |
| 2020-04-04 10:18:00 | SR-/- mice exhibited similar baseline intracranial self-stimulation thresholds but were less sensitive to the threshold-lowering (rewarding) and the performance-elevating (stimulant) effects of cocaine. While basal DA and glutamate release were elevated in the nucleus accumbens of SR-/- mice, cocaine-induced increases in DA and glutamate release were blunted. GABA efflux was unaffected in the SR-/- mice. | 29168271 |
| 2019-06-23 00:15:00 | The studies findings demonstrate neuronal serine racemase association with DISC1 and its agglomerates, which can be modulated by d-Serine. | 30391323 |
| 2019-02-16 10:45:00 | Serine racemase (SR) deficiency significantly prevented retinal ganglion cell (RGC) loss in diabetic mice. We conclude that D-serine is a critical factor in the degeneration of RGC in diabetic retinopathy (DR). Targeting SR expression or activity may be a strategy for ameliorating RGC loss in DR. | 29913163 |
| Type | IDs |
|---|---|
| Synonymous | M100034, Rgsc34, Srs |
| Gene |
UniProtKB-ID:
SRR_MOUSE
UniprotKB:
Q9QZX7
UniParc:
UPI00000E92DE,
UPI0000004050,
UPI00004704B6
EMBL:
AK170096,
AL604066,
BC011164,
AB235396,
AB232341,
AK043738,
AB232340,
AB232342,
AK028034,
AK157122,
AK031687,
AF148321,
AB232343
Ensembl:
ENSMUSG00000001323
KO:
mmu:27364
|
| Nucleutide sequences |
EMBL-CDS:
CAI24253.1,
AAH11164.1,
BAE19923.1,
AAF08701.1,
BAE41561.1,
CAI24254.1,
BAC25712.1,
BAE19922.1,
CAI24252.1,
BAE19921.1,
CAI24255.1,
BAE33968.1,
BAE19920.1,
BAE44529.1,
BAC27514.1,
BAC31637.1
Ensembl_TRS:
ENSMUST00000065211,
ENSMUST00000108447,
ENSMUST00000108448,
ENSMUST00000128556,
ENSMUST00000121738
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000113372,
ENSMUSP00000120012,
ENSMUSP00000104086,
ENSMUSP00000104087,
ENSMUSP00000067552
RefSeq:
XP_011247359.1,
XP_030101906.1,
NP_001349673.1,
XP_017170060.1,
NP_001349672.1,
XP_036012631.1,
XP_030101905.1,
NP_001349671.1,
NP_001156783.1,
NP_038789.1,
XP_006533520.1
|
| Others |
UniRef100:
UniRef100_Q9QZX7
UniRef90:
UniRef90_Q9QZX7
UniRef50:
UniRef50_Q9QZX7
UniGene:
Mm.131443,
Mm.220843,
Mm.412219
CCDS:
CCDS25038.1,
CCDS88190.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员