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27350 APOBEC3C

27350

APOBEC3C

apolipoprotein B mRNA editing enzyme catalytic subunit 3C

protein-coding

Homo sapiens

基因描述

Type Description
Definition apolipoprotein B mRNA editing enzyme catalytic subunit 3C

研究结论

Date Results Publications
2021-03-06 13:26:00 Loop 1 of APOBEC3C Regulates its Antiviral Activity against HIV-1. 33068636
2020-06-06 11:22:00 genetic variations in APOBEC3 genes may affect the efficiency of hepatitis b virus elimination in humans. 31400856
2019-04-27 10:26:00 A3C-Ile188 is capable of inhibiting Vif-deficient HIV-1 replication in T cells 30558640
2017-08-26 12:00:00 Data suggest that heat shock proteins, in particular Hsp90, stimulate APOBEC3-mediated DNA deamination activity toward hepatitis B viral DNA, suggesting a potential physiological role in mutagenesis/carcinogenesis and viral innate immunity; Hsp90 stimulates deamination activity of APOBEC3G, APOBEC3B, and APOBEC3C during co-expression in human liver HepG2 cells. 28637869
2017-05-20 14:30:00 our results suggest that APOBEC3C is in fact involved in protecting hosts from lentiviruses. 27732658

名称对应

Type IDs
Synonymous A3C, APOBEC1L, ARDC2, ARDC4, ARP5, PBI, bK150C2.3
Gene
UniProtKB-ID: ABC3C_HUMAN
UniprotKB: Q9NRW3
UniParc: UPI0000149A97
EMBL: CH471095, AF165520, BC021080, AK313272, CR456394, AL022318, BC011739
Ensembl: ENSG00000244509
KO: hsa:27350
Nucleutide sequences
EMBL-CDS: BAG36081.1, EAW60284.1, AAF86650.1, AAH11739.1, CAG30280.1
Ensembl_TRS: ENST00000361441
Protein sequencees
Ensembl_PRO: ENSP00000355340
RefSeq: NP_055323.2, XP_024307986.1
Others
UniRef100: UniRef100_Q9NRW3
UniRef90: UniRef90_Q9NRW3
UniRef50: UniRef50_Q9NRW3
UniGene: Hs.441124
CCDS: CCDS13983.1

全选

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