| Type | Description |
|---|---|
| Definition | potassium calcium-activated channel subfamily M regulatory beta subunit 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-30 12:10:00 | This study presents cryo-EM structures of Slo1 in complex with the auxiliary protein, beta4. Four beta4, each containing two transmembrane helices, encircle Slo1, contacting it through helical interactions inside the membrane. | 31815672 |
| 2015-11-07 11:29:00 | Two recurrent fusion genes associated with the 12q locus, LRP1-SNRNP25 and KCNMB4-CCND3, were by RT-PCR, Sanger sequencing and FISH, and were found to be osteosarcoma specific in a validation cohort of 240 other sarcomas. | 25300797 |
| 2015-01-03 11:42:00 | Recombinant martentoxin selectively blocks KCNMA1/KCNMB4 channels. | 24759175 |
| 2014-12-27 12:58:00 | BK channel beta4 subunit influences sensitivity and tolerance to alcohol by altering its response to kinases | 25190810 |
| 2014-11-08 13:13:00 | Study shows that beta4 subunit of the MaxiK channel has no potential endocytic signal and 2 specific amino acids in the functional basic motif retention/retrieval trafficking signal at the C-terminus may play a role in controlling cellular excitability | 24486049 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
KCMB4_HUMAN
UniprotKB:
Q86W47
UniParc:
UPI0000073E0E
EMBL:
AF215891,
BC042446,
AF207992,
AF170917,
BC050621,
AF160967
Ensembl:
ENSG00000135643
KO:
hsa:27345
|
| Nucleutide sequences |
EMBL-CDS:
AAF89699.1,
AAF69805.1,
AAH42446.2,
AAH50621.2,
AAF28333.1,
AAF75596.1
Ensembl_TRS:
ENST00000258111
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000258111
RefSeq:
XP_011536490.1,
NP_055320.4
|
| Others |
UniRef100:
UniRef100_Q86W47
UniRef90:
UniRef90_Q86W47
UniRef50:
UniRef50_Q86W47
UniGene:
Hs.525529
CCDS:
CCDS8997.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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