| Type | Description |
|---|---|
| Definition | DNA polymerase lambda |
| Date | Results | Publications |
|---|---|---|
| 2019-01-19 11:16:00 | PAXX, XLF and XRCC4 synergise in the efficient DNA double-strand breaks recruitment, substrate recognition and stimulation of Pol lambda enzymatic activity during nonhomologous end joining DNA repair. | 30250067 |
| 2018-04-28 10:51:00 | Bond formation and cleavage reactions catalyzed by base excision repair DNA polymerases beta and lambda has been described. | 27992186 |
| 2017-12-30 11:04:00 | When mutated or deregulated, DNA polymerase lambda can also be a source of genetic instability. Its multiple roles in DNA damage tolerance and its ability in promoting tumor progression make it also a possible target for novel anticancer approaches. [review] | 28841305 |
| 2017-08-12 11:47:00 | Data suggest that individuals who carry the rs3730477 POLL germline variant have an increased risk of estrogen-associated breast cancer. | 27621267 |
| 2017-07-29 12:15:00 | T204 was identified as a main target for ATM/DNA-PKcs phosphorylation on human POLL, and this phosphorylation may facilitate the repair of a subset of IR-induced DSBs and the efficient POLL-mediated gap-filling during NHEJ. POLL phosphorylation might favor POLL interaction with the DNA-PK complex at DSBs. | 28109743 |
| Type | IDs |
|---|---|
| Synonymous | BETAN, POLKAPPA |
| Gene |
UniProtKB-ID:
DPOLL_HUMAN,
A8K860_HUMAN,
B4DE17_HUMAN
UniprotKB:
Q9UGP5,
A8K860,
B4DE17
UniParc:
UPI00001F95B9,
UPI00015DA92A,
UPI00000398A1,
UPI000003EFFD
EMBL:
AK022476,
AF525924,
CH471066,
AF283478,
AL627424,
AK292225,
AJ131890,
AF161019,
AK293421,
BC068529,
BC003548
Ensembl:
ENSG00000166169
KO:
hsa:27343
|
| Nucleutide sequences |
EMBL-CDS:
AAH03548.2,
AAH68529.1,
AAG22519.1,
EAW49768.1,
EAW49760.1,
BAB14050.1,
CAB65074.1,
EAW49759.1,
EAW49766.1,
AAM77696.1,
AAF27541.1,
BAF84914.1,
BAG56928.1
Ensembl_TRS:
ENST00000299206,
ENST00000370162,
ENST00000370169,
ENST00000628479
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000359188,
ENSP00000299206,
ENSP00000485885,
ENSP00000359181
RefSeq:
XP_011537967.1,
XP_016871580.1,
XP_006717840.1,
XP_011537968.1,
XP_011537957.1,
XP_024303713.1,
XP_016871582.1,
XP_011537952.1,
XP_011537965.1,
XP_006717839.1,
XP_024303711.1,
XP_006717838.1,
XP_016871576.1,
XP_016871579.1,
XP_011537962.1,
XP_024303712.1,
XP_016871581.1,
XP_011537966.1,
XP_011537958.1,
NP_037406.1,
XP_016871573.1,
XP_011537969.1,
NP_001167555.1,
XP_016871578.1,
XP_011537959.1,
NP_001295311.1,
XP_011537953.1,
XP_011537955.1,
XP_011537954.1,
XP_016871574.1,
XP_016871575.1,
XP_016871577.1,
XP_011537956.1,
XP_024303710.1,
XP_011537964.1,
NP_001167556.1
|
| Others |
UniRef100:
UniRef100_A8K860,
UniRef100_Q9UGP5
UniRef90:
UniRef90_K7DF77,
UniRef90_Q9UGP5
UniRef50:
UniRef50_Q9QXE2,
UniRef50_Q9UGP5
UniGene:
Hs.523230
CCDS:
CCDS7513.1,
CCDS76332.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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