| Type | Description |
|---|---|
| Definition | TOX high mobility group box family member 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-10-31 13:13:00 | TOX3 gene variant could be associated with painful restless legs. | 31706190 |
| 2020-06-27 12:16:00 | TOX high mobility group box family member 3 (TOX3) is one such gene, in which SNPs have been found to be associated with breast cancer. Found nine SNPs that may affect the gene regulation. | 31819019 |
| 2020-04-18 12:38:00 | the TOX3 rs3803662 C>T polymorphism may not be associated with recurrent miscarriage in the southern Chinese population. | 31454102 |
| 2020-01-25 14:47:00 | Study identified TOX3 as a novel cancer suppressor gene in clear cell renal cell carcinoma (ccRCC). Hypermethylation in the promoter region was associated with its functional loss and poor outcome in ccRCC patients. Downregulation of TOX3 could accelerate the EMT by decreasing transcriptional repression of SNAI1 and SNAI2. Its overexpression inhibited RCC cell growth, migration and invasion. | 30772441 |
| 2019-07-13 11:49:00 | TOX3-rs3803662, may confer some degrees of risk of breast cancer in Iranian population. | 30515698 |
| Type | IDs |
|---|---|
| Synonymous | CAGF9, TNRC9 |
| Gene |
UniProtKB-ID:
TOX3_HUMAN
UniprotKB:
O15405
UniParc:
UPI00001972E7,
UPI0000DD835C
EMBL:
U80736,
AK299202,
AC007490
Ensembl:
ENSG00000103460
KO:
hsa:27324
|
| Nucleutide sequences |
EMBL-CDS:
AAB91435.1,
BAG61242.1
Ensembl_TRS:
ENST00000407228,
ENST00000219746
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000219746,
ENSP00000385705
RefSeq:
XP_016878631.1,
NP_001073899.2,
XP_024305998.1,
NP_001139660.1,
XP_011521304.1,
XP_005255949.1
|
| Others |
UniRef100:
UniRef100_O15405
UniRef90:
UniRef90_O15405
UniRef50:
UniRef50_O15405
UniGene:
Hs.460789
CCDS:
CCDS54008.1,
CCDS54009.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员