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27316 RBMX

27316

RBMX

RNA binding motif protein X-linked

protein-coding

Homo sapiens

基因描述

Type Description
Definition RNA binding motif protein X-linked

研究结论

Date Results Publications
2020-02-22 12:26:00 hnRNPG associates co-transcriptionally with RNAPII and regulates alternative splicing transcriptome-wide. m(6)A near splice sites in nascent pre-mRNA modulates hnRNPG binding, which influences RNAPII occupancy patterns and promotes exon inclusion. 31445886
2020-02-01 11:27:00 PUM binding is required for maintenance of genomic stability by NORAD whereas binding of RBMX is dispensable for this function. 31343408
2019-06-15 10:18:00 Study demonstrates a novel role for the splice factor hnRNPG in the pregnant myometrium. hnRNPG is required for the exclusion of exon 7 in the derivation of the dominant negative myometrial ERDelta7 isoform and is negatively regulated in an E2 dependent manner. 30502052
2018-09-29 12:22:00 These results suggest that satellite I RNA plays a role in stabilizing RBMX and Sororin in the ncRNP complex to maintain proper sister chromatid cohesion. 29383807
2017-10-07 12:53:00 HNRNPG binds m6A-methylated RNAs through its C-terminal low-complexity region, which self-assembles into large particles in vitro. The Arg-Gly-Gly repeats within the low-complexity region are required for binding to the RNA motif exposed by m6A methylation. 28334903

名称对应

Type IDs
Synonymous HNRNPG, HNRPG, MRXS11, RBMXP1, RBMXRT, RNMX, hnRNP-G
Gene
UniProtKB-ID: RBMX_HUMAN
UniprotKB: P38159
UniParc: UPI00017A88D6, UPI0000072512, UPI0000134535
EMBL: Z23064, BC006550, AF266723, AF266721, AY464692, AF266722, AK304868, AL683813, AK096015, AF266720, CH471150, BC007435
Ensembl: ENSG00000147274
KO: hsa:27316
Nucleutide sequences
EMBL-CDS: BAC04674.1, BAG65606.1, CAA80599.1, EAW88454.1, AAH06550.1, AAK58567.1, EAW88455.1, EAW88453.1, EAW88457.1, AAR28036.1, AAH07435.1
Ensembl_TRS: ENST00000320676, ENST00000431446
Protein sequencees
Ensembl_PRO: ENSP00000411989, ENSP00000359645
RefSeq: NP_002130.2, NP_001158275.1
Others
UniRef100: UniRef100_P38159
UniRef90: UniRef90_P38159
UniRef50: UniRef50_P38159
UniGene: Hs.380118, Hs.710162
CCDS: CCDS14661.1, CCDS55510.1

全选

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