| Type | Description |
|---|---|
| Definition | glycine decarboxylase |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 11:13:00 | GLDC overexpression significantly induced cell autophagy, whereas GLDC downregulation reduced cell autophagy. Of note, GLDC is the post-transcriptional target of miR-30d-5p. GLDC overexpression could rescue miR-30d-5p-mediated cell metastasis and increase autophagy. | 30804330 |
| 2020-04-18 12:25:00 | we identified a new alternative splicing isoform of GLDC, truncated GLDCV1, and demonstrated that GLDCV1 possesses similar biological activities to GLDCfl on regulating CSCs and tumorigenesis. | 31773974 |
| 2020-03-14 11:16:00 | These findings reveal a critical role of GLDC in sustaining the proliferation of neuroblastoma cells with high-level GLDC expression and suggest that MYCN amplification is a biomarker for GLDC-based therapeutic strategies against high-risk neuroblastoma. | 31444411 |
| 2019-08-10 12:04:00 | Collectively, GLDC regulates cellular antiviral response and orchestrates viral growth. GLDC is a functional susceptibility gene to severe influenza in humans. | 30498026 |
| 2019-07-20 11:06:00 | these findings suggest that GLDC-mediated regulation of glycolysis and controlling AGE accumulation is related to maintenance and induction of pluripotency. | 30779965 |
| Type | IDs |
|---|---|
| Synonymous | GCE, GCSP, HYGN1 |
| Gene |
UniProtKB-ID:
GCSP_HUMAN
UniprotKB:
P23378
UniParc:
UPI0000684276
EMBL:
AK314156,
BC111993,
BC111995,
CH471071,
D90239,
M64590,
AL162411,
AL353718,
M63635
Ensembl:
ENSG00000178445
KO:
hsa:2731
|
| Nucleutide sequences |
EMBL-CDS:
BAA14286.1,
EAW58740.1,
BAG36841.1,
AAA36463.1,
AAI11996.1,
AAA36478.1,
AAI11994.1
Ensembl_TRS:
ENST00000321612
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370737
RefSeq:
NP_000161.2
|
| Others |
UniRef100:
UniRef100_P23378
UniRef90:
UniRef90_P23378
UniRef50:
UniRef50_P23378
UniGene:
Hs.584238
CCDS:
CCDS34987.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员