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27306 HPGDS

27306

HPGDS

hematopoietic prostaglandin D synthase

protein-coding

Homo sapiens

基因描述

Type Description
Definition hematopoietic prostaglandin D synthase

研究结论

Date Results Publications
2017-11-26 00:34:00 we have utilized a broad-scaled affinity proteomics approach to identify three proteins (CCL5, HPGDS, and NPSR1) with altered plasma levels in asthmatic children compared to healthy controls, representing the first evaluation of HPGDS and NPSR1 in plasma. 27145233
2017-05-13 21:39:00 the development of a competition binding assay amenable to high-throughput screening (HTS) in a scintillation proximity assay format. This assay was used to screen an in-house compound library of approximately 280,000 compounds for novel H-PGDS inhibitors. 27485270
2014-10-25 12:16:00 The effect of C. molle alkaloid extract on H-PGDS was studied. The alkaloid extract exhibited a 70% inhibition on H-PGDS with an IC50 of 13.7 mug/ml. 24996417
2012-08-25 11:05:00 the Val187Ile HPGDS isoenzyme common among African Americans is not associated with colorectal cancer risk 21821144
2012-04-21 10:26:00 COX-1 and H-PGDS were rapidly ubiquitinated and degraded through the ubiquitin-proteasome system in response to the elevation of the intracellular calcium level 22049022

名称对应

Type IDs
Synonymous GSTS, GSTS1, GSTS1-1, PGD2, PGDS
Gene
UniProtKB-ID: HPGDS_HUMAN, A0A384P5J0_HUMAN
UniprotKB: O60760, A0A384P5J0
UniParc: UPI0000157E08
EMBL: D82073, AK290075, BC020734, CR541679, CH471057, CR541662, AB008830, GQ891393
Ensembl: ENSG00000163106
KO: hsa:27306
Nucleutide sequences
EMBL-CDS: CAG46480.1, BAA96854.1, EAX06052.1, AAH20734.1, CAG46463.1, BAF82764.1, BAA25545.1, ADO22255.1
Ensembl_TRS: ENST00000295256
Protein sequencees
Ensembl_PRO: ENSP00000295256
RefSeq: XP_005262989.1, NP_055300.1
Others
UniRef100: UniRef100_O60760
UniRef90: UniRef90_O60760
UniRef50: UniRef50_O60760
UniGene: Hs.128433
CCDS: CCDS3640.1

全选

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