| Type | Description |
|---|---|
| Definition | amphiphysin |
| Date | Results | Publications |
|---|---|---|
| 2019-05-04 10:24:00 | the anti-oncogenic function of AMPH-1 in lung cancer in vitro and in vivo, is reported. | 30143925 |
| 2018-09-01 10:36:00 | The data show that the dynamin-amphiphysin helices are rearranged to form clusters upon GTP hydrolysis and membrane constriction occurs at protein-uncoated regions flanking the clusters. | 29357276 |
| 2016-02-13 10:58:00 | We show that AMPH-1/BIN1 binds to nesprin and actin, as well as to the microtubule-binding protein CLIP170 in both species. We propose that BIN1 has a direct and evolutionarily conserved role in nuclear positioning, altered in myopathies. | 26506308 |
| 2015-04-18 12:02:00 | It is a nerve protein and its autoantibody causes paraneoplastic neurological syndromes. | 25087559 |
| 2013-07-20 10:09:00 | AMPH1 protein level is reduced in transgenic mouse brain proteins. in the brainstem of nontransgenic and terminally ill JNPL3 transgenic mice. | 22975846 |
| Type | IDs |
|---|---|
| Synonymous | AMPH1 |
| Gene |
UniProtKB-ID:
AMPH_HUMAN
UniprotKB:
P49418
UniParc:
UPI00001259EA,
UPI000002A3B8
EMBL:
CH471073,
AC012490,
AC011309,
X81438,
U07616,
AC007245,
CH236951,
AF034996,
BC034376
Ensembl:
ENSG00000078053
KO:
hsa:273
|
| Nucleutide sequences |
EMBL-CDS:
EAL23990.1,
AAS07541.1,
EAL23989.1,
AAA21865.1,
AAH34376.1,
AAC02977.1,
AAS07563.1,
AAS07391.1,
EAW94111.1,
CAA57197.1,
EAW94110.1
Ensembl_TRS:
ENST00000356264,
ENST00000325590
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000348602,
ENSP00000317441
RefSeq:
XP_011513573.1,
XP_016867484.1,
NP_647477.1,
NP_001626.1,
XP_006715752.1,
XP_006715753.1,
XP_006715754.1,
XP_016867485.1
|
| Others |
UniRef100:
UniRef100_P49418
UniRef90:
UniRef90_P49418
UniRef50:
UniRef50_P49418
UniGene:
Hs.592182
CCDS:
CCDS47574.1,
CCDS5456.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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