| Type | Description |
|---|---|
| Definition | ADAM like decysin 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-22 15:25:00 | ADAMDEC1 Maintains a Growth Factor Signaling Loop in Cancer Stem Cells. | 31434712 |
| 2020-07-11 10:20:00 | The ADAMDEC1 plays a pro-inflammatory role in rosacea via modulating the M1 polarization of macrophages. | 31627897 |
| 2019-10-19 12:26:00 | ADAMDEC1 is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells | 29941981 |
| 2019-05-04 11:49:00 | Data show the critical pathways regulating the expression of ADAMDEC1 and the roles of enhancer RNAs and mechanistically links E1A binding protein p300 (p300) and enhancer RNAs, which is dependent on NF-kappa B (NFkappaB). | 30352365 |
| 2017-07-08 12:40:00 | Data suggest that activated platelets release ADAMDEC1, which hydrolyzes pro-EGF (epidermal growth factor) to soluble, active HMW-EGF; proteolytic cleavage of pro-EGF first occurs at the C-terminal arginyl residue of the EGF domain; proteolysis is the regulated, rate-limiting step in generating soluble EGF from activated platelets. | 28455445 |
| Type | IDs |
|---|---|
| Synonymous | M12.219 |
| Gene |
UniProtKB-ID:
ADEC1_HUMAN,
B7Z6V5_HUMAN
UniprotKB:
O15204,
B7Z6V5
UniParc:
UPI00019150DB,
UPI00019153ED,
UPI0000073385
EMBL:
Y13323,
BC074877,
AK316322,
BC074878,
BC069582,
AC120193,
AK316320,
AK301007
Ensembl:
ENSG00000134028
KO:
hsa:27299
|
| Nucleutide sequences |
EMBL-CDS:
BAH14691.1,
AAH69582.1,
BAH14693.1,
CAA73764.2,
AAH74878.1,
AAH74877.1,
BAH13391.1
Ensembl_TRS:
ENST00000522298,
ENST00000256412
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000428993,
ENSP00000256412
RefSeq:
NP_001138743.1,
NP_001138744.1,
NP_055294.1
|
| Others |
UniRef100:
UniRef100_O15204,
UniRef100_B7Z6V5
UniRef90:
UniRef90_O15204
UniRef50:
UniRef50_O15204
UniGene:
Hs.521459
CCDS:
CCDS6044.1,
CCDS55212.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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