Type | Description |
---|---|
Definition | CGRP receptor component |
Date | Results | Publications |
---|---|---|
2020-03-21 10:39:00 | both anti-CGRP and anti-CGRP receptor monoclonal antibodies (mABs) completed clinical development, and the first representatives of these 2 classes are available on the market. MABs are approved for prevention of migraine attacks in chronic or episodic migraine, involving long-term treatments. | 31018157 |
2017-07-22 10:30:00 | data reinforce and clarify our understanding of CGRP receptor localization, and provide evidence that antagonist antibodies bind to target sites in the trigeminovascular system of primates that are involved in the pathology of migraine | 27155150 |
2017-05-27 11:24:00 | CGRP family of receptors displays both ligand- and RAMP-dependent signaling bias among the Galphas, Galphai, and Galphaq/11 pathways. | 27566546 |
2014-12-06 12:01:00 | In this review, the influence of the CGRP family peptides in reproduction and pregnancy is explored and discussed. | 25015815 |
2012-06-23 11:13:00 | This study demonstrates the detailed expression of CGRP and its receptor components within spinal trigeminal nucleus in the brainstem and in the spinal cord at C1-level | 22074408 |
Type | IDs |
---|---|
Synonymous | CGRP-RCP, CGRPRCP, RCP, RCP9, RPC9 |
Gene |
UniProtKB-ID:
RPC9_HUMAN,
A0A024RDL0_HUMAN
UniprotKB:
O75575,
A0A024RDL0
UniParc:
UPI0000074384,
UPI0000128406,
UPI00004DF8F2,
UPI00017A8864
EMBL:
BP233211,
AF073792,
BC040107,
AC068533,
CH471140,
BC105808,
BX647867,
U51134,
AK303737,
AK290553,
AK311829
Ensembl:
ENSG00000241258
KO:
hsa:27297
|
Nucleutide sequences |
EMBL-CDS:
BAG34771.1,
EAX07941.1,
AAH40107.1,
BAG64710.1,
BAF83242.1,
AAD05036.1,
AAI05809.1,
AAC25992.1,
CAI46069.1,
EAX07943.1
Gene_ORFName:
hCG_18703
Ensembl_TRS:
ENST00000431089,
ENST00000398684,
ENST00000395326,
ENST00000338592
|
Protein sequencees |
Ensembl_PRO:
ENSP00000378736,
ENSP00000340044,
ENSP00000381674,
ENSP00000388653
RefSeq:
NP_001035737.1,
NP_055293.1,
NP_001135886.1,
NP_001035738.1
|
Others |
UniRef100:
UniRef100_O75575
UniRef90:
UniRef90_O75575
UniRef50:
UniRef50_O75575
UniGene:
Hs.300684
CCDS:
CCDS55116.1,
CCDS5532.1,
CCDS47599.1,
CCDS47600.1
|
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